Drug Release Kinetics from Polymer Matrix through Fractal Approximation of Motion
Joint Authors
Popa, M.
Agop, Maricel
Urîtu, C.
Peptu, C.
Băcăiţă, S.
Uliniuc, A.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-13
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Engineering Sciences and Information Technology
Abstract EN
The present paper analyzes the process of drug release from polymer matrix.
This process has been considered as fractal polymer process.
Since complexity of physical processes is replaced by fractality, the paper studies the process through fractal approach.
In drug dynamics, fractal “diffusion” equation can be obtained through fractal approximation of motion.
All experimental release curves have been best demonstrated by Weibull relation (which was, in its turn, also demonstrated).
Weibull parameters are related to the fractal dimension of drug release kinetics from a polymer matrix.
Such a dimension can characterize and measure the complexity of the system.
In the above-mentioned context, some experimental results of our researchers are presented and analyzed by comparing them with Peppas relation, a basic law in the description of drug release kinetics.
Consequently, experimental data for Weibull relation are better correlated with certain resulting factors.
At the same time, some conclusions regarding the phenomena involved in the process are considered as being based on the approach.
American Psychological Association (APA)
Băcăiţă, S.& Urîtu, C.& Popa, M.& Uliniuc, A.& Peptu, C.& Agop, Maricel. 2012. Drug Release Kinetics from Polymer Matrix through Fractal Approximation of Motion. Smart Materials Research،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-458659
Modern Language Association (MLA)
Băcăiţă, S.…[et al.]. Drug Release Kinetics from Polymer Matrix through Fractal Approximation of Motion. Smart Materials Research No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-458659
American Medical Association (AMA)
Băcăiţă, S.& Urîtu, C.& Popa, M.& Uliniuc, A.& Peptu, C.& Agop, Maricel. Drug Release Kinetics from Polymer Matrix through Fractal Approximation of Motion. Smart Materials Research. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-458659
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458659