Measurement of Photoreceptor Layer in Glaucoma : A Spectral-Domain Optical Coherence Tomography Study
Joint Authors
Leung, Christopher Kai-shun
Fan, Ning
Lam, Dennis Shun Chiu
Huang, Nina
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-10
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
To measure and compare photoreceptor layer thickness between normal and glaucomatous eyes using spectral-domain optical coherence tomography (OCT).
Methods.
Thirty-eight healthy normal volunteers and 47 glaucoma patients were included in the analysis.
One eye from each participant was randomly selected for macula imaging by a spectral-domain OCT (3D OCT-1000, Topcon, Tokyo, Japan).
The foveal and parafoveal (1.5 mm from the fovea) outer nuclear layer (ONL) and inner and outer segments (IS+OS) layer thicknesses were measured by a single masked observer.
The measurements were repeated 3 times in a random sample of 30 normal eyes to determine the repeatability coefficient and intraclass correlation coefficient.
Results.
The measurement variabilities of photoreceptor thickness were low.
The respective intraclass correlation coefficients of ONL and IS+OS thicknesses were 0.96 (95% confidence interval: 0.94–0.98) and 0.82 (95% confidence interval 0.70–0.90).
While there were no differences in parafoveal ONL and IS+OS thicknesses between normal and glaucoma groups (P≤.410), the foveal ONL thickness was greater in glaucomatous eyes (P=.011) than in normal eyes.
Conclusions.
Glaucomatous damage may involve structural change in the photoreceptor layer.
American Psychological Association (APA)
Fan, Ning& Huang, Nina& Lam, Dennis Shun Chiu& Leung, Christopher Kai-shun. 2011. Measurement of Photoreceptor Layer in Glaucoma : A Spectral-Domain Optical Coherence Tomography Study. Journal of Ophthalmology،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-458676
Modern Language Association (MLA)
Fan, Ning…[et al.]. Measurement of Photoreceptor Layer in Glaucoma : A Spectral-Domain Optical Coherence Tomography Study. Journal of Ophthalmology No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-458676
American Medical Association (AMA)
Fan, Ning& Huang, Nina& Lam, Dennis Shun Chiu& Leung, Christopher Kai-shun. Measurement of Photoreceptor Layer in Glaucoma : A Spectral-Domain Optical Coherence Tomography Study. Journal of Ophthalmology. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-458676
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458676