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Autoantibodies to Tumor-Associated Antigens in Breast Carcinoma
Joint Authors
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-11-21
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Autoantibodies (AAbs) to tumor-associated antigens (TAAs) have been identified in the circulation of patients with cancer.
This paper will focus on recent knowledge related to circulating AAbs to TAAs in breast carcinoma.
So far, the following TAAs have been identified to elicit circulating AAbs in breast carcinoma: p53, MUC-1, heat shock proteins (HSP-27, HSP-60, and HSP-90), HER2/neu/c-erb B2, GIPC-1, c-myc, c-myb, cancer-testis antigens (NY-ESO-1), BRCA1, BRCA2, endostatin, lipophilin B, cyclin B1, cyclin D1, fibulin, insulin-like growth factor binding protein 2 (IGFBP-2), topoisomerase II alpha (TOPO2α), and cathepsin D.
Measurement of serum AAbs to one specific TAA only is of little value for screening and early diagnosis of breast carcinoma; however, assessment of AAbs to a panel of TAAs may have promising diagnostic potential.
American Psychological Association (APA)
Piura, Ettie& Piura, Benjamin. 2010. Autoantibodies to Tumor-Associated Antigens in Breast Carcinoma. Journal of Oncology،Vol. 2010, no. 2010, pp.1-14.
https://search.emarefa.net/detail/BIM-458690
Modern Language Association (MLA)
Piura, Ettie& Piura, Benjamin. Autoantibodies to Tumor-Associated Antigens in Breast Carcinoma. Journal of Oncology No. 2010 (2010), pp.1-14.
https://search.emarefa.net/detail/BIM-458690
American Medical Association (AMA)
Piura, Ettie& Piura, Benjamin. Autoantibodies to Tumor-Associated Antigens in Breast Carcinoma. Journal of Oncology. 2010. Vol. 2010, no. 2010, pp.1-14.
https://search.emarefa.net/detail/BIM-458690
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458690