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Biomarkers of Radiosensitivity in A-Bomb Survivors Pregnant at the Time of Bombings in Hiroshima and Nagasaki
Joint Authors
Nakachi, Kei
Kodama, Yoshiaki
Funamoto, Sachiyo
Fujiwara, Saeko
Seed, Thomas
Tatsukawa, Yoshimi
Miles, Edward F.
Kusonoki, Yoichiro
Kamada, Naoko
Akahoshi, Masazumi
Nakashima, Eiji
Neriishi, Kazuo
Source
ISRN Obstetrics and Gynecology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-09-29
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Purpose.
There is evidence in the literature of increased maternal radiosensitivity during pregnancy.
Materials and Methods.
We tested this hypothesis using information from the atomic-bomb survivor cohort, that is, the Adult Health Study database at the Radiation Effects Research Foundation, which contains data from a cohort of women who were pregnant at the time of the bombings of Hiroshima and Nagasaki.
Previous evaluation has demonstrated long-term radiation dose-response effects.
Results/Conclusions.
Data on approximately 250 women were available to assess dose-response rates for serum cholesterol, white blood cell count, erythrocyte sedimentation rate, and serum hemoglobin, and on approximately 85 women for stable chromosome aberrations, glycophorin A locus mutations, and naïve CD4 T-cell counts.
Although there is no statistically significant evidence of increased radiosensitivity in pregnant women, the increased slope of the linear trend line in the third trimester with respect to stable chromosome aberrations is suggestive of an increased radiosensitivity.
American Psychological Association (APA)
Miles, Edward F.& Tatsukawa, Yoshimi& Funamoto, Sachiyo& Kamada, Naoko& Nakashima, Eiji& Kodama, Yoshiaki…[et al.]. 2010. Biomarkers of Radiosensitivity in A-Bomb Survivors Pregnant at the Time of Bombings in Hiroshima and Nagasaki. ISRN Obstetrics and Gynecology،Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-458695
Modern Language Association (MLA)
Miles, Edward F.…[et al.]. Biomarkers of Radiosensitivity in A-Bomb Survivors Pregnant at the Time of Bombings in Hiroshima and Nagasaki. ISRN Obstetrics and Gynecology No. 2011 (2011), pp.1-11.
https://search.emarefa.net/detail/BIM-458695
American Medical Association (AMA)
Miles, Edward F.& Tatsukawa, Yoshimi& Funamoto, Sachiyo& Kamada, Naoko& Nakashima, Eiji& Kodama, Yoshiaki…[et al.]. Biomarkers of Radiosensitivity in A-Bomb Survivors Pregnant at the Time of Bombings in Hiroshima and Nagasaki. ISRN Obstetrics and Gynecology. 2010. Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-458695
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458695