The Onset of Enhanced Intestinal Permeability and Food Sensitivity Triggered by Medication Used in Dental Procedures : A Case Report

Joint Authors

Lambert, Jama
Vojdani, Aristo

Source

Case Reports in Gastrointestinal Medicine

Issue

Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-3, 3 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2012-09-12

Country of Publication

Egypt

No. of Pages

3

Main Subjects

Diseases

Abstract EN

Enhanced intestinal permeability and food sensitivity are two of the many proven causes of gastrointestinal disorders.

This present report describes a woman with no previous gastrointestinal (GI) complaints, who underwent dental root canal, bone graft, and implant procedures.

Postsurgery she experienced an allergic reaction to the combined medications.

In the weeks that followed, she presented with multiple food intolerances.

Four weeks after the final dental procedure, she was assessed serologically for mucosal immune function, salivary, and blood-gluten reactivity, intestinal permeability, and other food sensitivities.

Compared to her test reports from two months prior to her first dental procedure, the patient’s results showed high total secretory IgA (SIgA) and elevated salivary antibodies to alpha-gliadin, indicating abnormal mucosal immunity and loss of tolerance to gluten.

Her serologic assessments revealed immunoglobulin G (IgG) and IgA antibodies to a range of wheat/gluten proteins and peptides, gut bacterial endotoxins and tight junction proteins.

These test results indicate gut dysbiosis, enhanced intestinal permeability, systemic gluten-reactivity, and immune response to other dietary macromolecules.

The present case suggests that patients who experience severe allergic or pseudoallergic reactions to medication should be assessed and monitored for gut dysfunction.

If left untreated this could lead to autoimmune reactions to self tissues.

American Psychological Association (APA)

Vojdani, Aristo& Lambert, Jama. 2012. The Onset of Enhanced Intestinal Permeability and Food Sensitivity Triggered by Medication Used in Dental Procedures : A Case Report. Case Reports in Gastrointestinal Medicine،Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-458700

Modern Language Association (MLA)

Vojdani, Aristo& Lambert, Jama. The Onset of Enhanced Intestinal Permeability and Food Sensitivity Triggered by Medication Used in Dental Procedures : A Case Report. Case Reports in Gastrointestinal Medicine No. 2012 (2012), pp.1-3.
https://search.emarefa.net/detail/BIM-458700

American Medical Association (AMA)

Vojdani, Aristo& Lambert, Jama. The Onset of Enhanced Intestinal Permeability and Food Sensitivity Triggered by Medication Used in Dental Procedures : A Case Report. Case Reports in Gastrointestinal Medicine. 2012. Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-458700

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-458700