Pathogens, Social Networks, and the Paradox of Transmission Scaling
Joint Authors
Perkins, Sarah E.
Ferrari, Matthew J.
Pomeroy, Laura W.
Bjørnstad, Ottar N.
Source
Interdisciplinary Perspectives on Infectious Diseases
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-09
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Understanding the scaling of transmission is critical to predicting how infectious diseases will affect populations of different sizes and densities.
The two classic “mean-field” epidemic models—either assuming density-dependent or frequency-dependent transmission—make predictions that are discordant with patterns seen in either within-population dynamics or across-population comparisons.
In this paper, we propose that the source of this inconsistency lies in the greatly simplifying “mean-field” assumption of transmission within a fully-mixed population.
Mixing in real populations is more accurately represented by a network of contacts, with interactions and infectious contacts confined to the local social neighborhood.
We use network models to show that density-dependent transmission on heterogeneous networks often leads to apparent frequency dependency in the scaling of transmission across populations of different sizes.
Network-methodology allows us to reconcile seemingly conflicting patterns of within- and across-population epidemiology.
American Psychological Association (APA)
Ferrari, Matthew J.& Perkins, Sarah E.& Pomeroy, Laura W.& Bjørnstad, Ottar N.. 2011. Pathogens, Social Networks, and the Paradox of Transmission Scaling. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-458784
Modern Language Association (MLA)
Ferrari, Matthew J.…[et al.]. Pathogens, Social Networks, and the Paradox of Transmission Scaling. Interdisciplinary Perspectives on Infectious Diseases No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-458784
American Medical Association (AMA)
Ferrari, Matthew J.& Perkins, Sarah E.& Pomeroy, Laura W.& Bjørnstad, Ottar N.. Pathogens, Social Networks, and the Paradox of Transmission Scaling. Interdisciplinary Perspectives on Infectious Diseases. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-458784
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458784