Pemphigoid Gestationis after Spontaneous Expulsion of a Massive Complete Hydatidiform Mole
Joint Authors
Takahashi, Sachio
Matsumoto, Chieko
Suzuki, Nagazumi
Osada, Marie
Udagawa, Haruhiko
Kaneko, Kou
Matsumoto, Naoki
Ohara, Ken
Noguchi, Daito
Source
Case Reports in Obstetrics and Gynecology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-08
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Pemphigoid gestationis (PG) is a rare, perinatal, autoimmune, and blistering dermatosis.
Only few cases of PG involving hydatidiform moles have been reported.
Complete hydatidiform moles are usually evacuated by dilatation and curettage.
We report a patient with a massive complete hydatidiform mole that underwent spontaneous expulsion; she subsequently developed PG.
A 19-year-old unmarried nulligravid woman was referred to our hospital following excessive vaginal bleeding after an uncertain amenorrheal period.
The patient presented with preshock vital signs, severe anemia, and a positive urine pregnancy test.
Imaging examinations revealed a massive intrauterine mass (19 × 15 × 10 cm), suggesting a complete hydatidiform mole.
She was hospitalized and treated with blood transfusion.
Sixteen hours after hospitalization, the massive molar mass underwent spontaneous expulsion and bleeding ceased.
Three days after the expulsion, she developed pruritic skin lesions including papules, erythemas, and bullae, which spread over her entire body.
Skin biopsy revealed PG and subepidermal blister formation and linear complement C3 deposition along the basement membrane zone, and the serum anti-BP180 antibody level was found to be high on measurement.
She was effectively treated with 50 mg/day of oral prednisolone.
Her skin lesions disappeared, leaving pigmentation.
American Psychological Association (APA)
Matsumoto, Naoki& Osada, Marie& Kaneko, Kou& Ohara, Ken& Noguchi, Daito& Udagawa, Haruhiko…[et al.]. 2013. Pemphigoid Gestationis after Spontaneous Expulsion of a Massive Complete Hydatidiform Mole. Case Reports in Obstetrics and Gynecology،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-458812
Modern Language Association (MLA)
Matsumoto, Naoki…[et al.]. Pemphigoid Gestationis after Spontaneous Expulsion of a Massive Complete Hydatidiform Mole. Case Reports in Obstetrics and Gynecology No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-458812
American Medical Association (AMA)
Matsumoto, Naoki& Osada, Marie& Kaneko, Kou& Ohara, Ken& Noguchi, Daito& Udagawa, Haruhiko…[et al.]. Pemphigoid Gestationis after Spontaneous Expulsion of a Massive Complete Hydatidiform Mole. Case Reports in Obstetrics and Gynecology. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-458812
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458812