Sentinel Lymph Node Biopsy in Nonmelanoma Skin Cancer Patients
Joint Authors
Boubaker, Ariane
Matthey-Giè, Marie-Laure
Matter, Maurice
Demartines, Nicolas
Letovanec, Igor
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-14
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The management of lymph nodes in nonmelanoma skin cancer patients is currently still debated.
Merkel cell carcinoma (MCC), squamous cell carcinoma (SCC), pigmented epithelioid melanocytoma (PEM), and other rare skin neoplasms have a well-known risk to spread to regional lymph nodes.
The use of sentinel lymph node biopsy (SLNB) could be a promising procedure to assess this risk in clinically N0 patients.
Metastatic SNs have been observed in 4.5–28% SCC (according to risk factors), in 9–42% MCC, and in 14–57% PEM.
We observed overall 30.8% positive SNs in 13 consecutive patients operated for high-risk nonmelanoma skin cancer between 2002 and 2011 in our institution.
These high rates support recommendation to implement SLNB for nonmelanoma skin cancer especially for SCC patients.
Completion lymph node dissection following positive SNs is also a matter of discussion especially in PEM.
It must be remembered that a definitive survival benefit of SLNB in melanoma patients has not been proven yet.
However, because of its low morbidity when compared to empiric elective lymph node dissection or radiation therapy of lymphatic basins, SLNB has allowed sparing a lot of morbidity and could therefore be used in nonmelanoma skin cancer patients, even though a significant impact on survival has not been demonstrated.
American Psychological Association (APA)
Matthey-Giè, Marie-Laure& Boubaker, Ariane& Letovanec, Igor& Demartines, Nicolas& Matter, Maurice. 2013. Sentinel Lymph Node Biopsy in Nonmelanoma Skin Cancer Patients. Journal of Skin Cancer،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-458834
Modern Language Association (MLA)
Matthey-Giè, Marie-Laure…[et al.]. Sentinel Lymph Node Biopsy in Nonmelanoma Skin Cancer Patients. Journal of Skin Cancer No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-458834
American Medical Association (AMA)
Matthey-Giè, Marie-Laure& Boubaker, Ariane& Letovanec, Igor& Demartines, Nicolas& Matter, Maurice. Sentinel Lymph Node Biopsy in Nonmelanoma Skin Cancer Patients. Journal of Skin Cancer. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-458834
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458834