Comparative Analysis of Protein Glycosylation Pathways in Humans and the Fungal Pathogen Candida albicans
Joint Authors
Díaz-Jímenez, Diana F.
Mora-Montes, Héctor M.
Martínez-Duncker, Iván
Source
International Journal of Microbiology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-02
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Abstract EN
Protein glycosylation pathways are present in all kingdoms of life and are metabolic pathways found in all the life kingdoms.
Despite sharing commonalities in their synthesis, glycans attached to glycoproteins have species-specific structures generated by the presence of different sets of enzymes and acceptor substrates in each organism.
In this review, we present a comparative analysis of the main glycosylation pathways shared by humans and the fungal pathogen Candida albicans: N-linked glycosylation, O-linked mannosylation and glycosylphosphatidylinositol-anchorage.
The knowledge of similarities and divergences between these metabolic pathways could help find new pharmacological targets for C.
albicans infection.
American Psychological Association (APA)
Martínez-Duncker, Iván& Díaz-Jímenez, Diana F.& Mora-Montes, Héctor M.. 2014. Comparative Analysis of Protein Glycosylation Pathways in Humans and the Fungal Pathogen Candida albicans. International Journal of Microbiology،Vol. 2014, no. 2014, pp.1-16.
https://search.emarefa.net/detail/BIM-458837
Modern Language Association (MLA)
Martínez-Duncker, Iván…[et al.]. Comparative Analysis of Protein Glycosylation Pathways in Humans and the Fungal Pathogen Candida albicans. International Journal of Microbiology No. 2014 (2014), pp.1-16.
https://search.emarefa.net/detail/BIM-458837
American Medical Association (AMA)
Martínez-Duncker, Iván& Díaz-Jímenez, Diana F.& Mora-Montes, Héctor M.. Comparative Analysis of Protein Glycosylation Pathways in Humans and the Fungal Pathogen Candida albicans. International Journal of Microbiology. 2014. Vol. 2014, no. 2014, pp.1-16.
https://search.emarefa.net/detail/BIM-458837
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458837