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Systemic Lupus Erythematosus Presenting as Thrombotic Thrombocytopenia Purpura : How Close Is Close Enough?
Joint Authors
Shrestha, Anuj
Santos, Edgardo S.
Abdo, Nabil
Perez, Cesar A.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-10
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Thrombotic thrombocytopenic purpura (TTP) is an uncommon life-threatening disease characterized by microangiopathic hemolytic anemia and thrombocytopenia, commonly associated with infections, malignancy, drugs, and autoimmune diseases.
We report a case of 19-year-old previously healthy female that presents with anemia and thrombocytopenia diagnosed with thrombotic thrombocytopenic purpura that was treated successfully with plasmapheresis and corticosteroids.
Laboratory findings also revealed antinuclear antibodies and antibodies to double-stranded DNA.
Two weeks after presentation developed inflammatory arthritis, fulfilling diagnostic criteria for systemic lupus erythematosus (SLE).
Prompt diagnosis and treatment with plasma exchange and corticosteroids should be instituted as soon as the diagnosis of TTP is suspected, even if other diagnoses, including lupus, are possible.
When present, the coexistence of these two etiologies can have a higher mortality than either disease alone.
An underlying diagnosis of SLE should be considered in all patients presenting TTP and the study of this association may provide a better understanding of their immune-mediated pathophysiology.
American Psychological Association (APA)
Perez, Cesar A.& Abdo, Nabil& Shrestha, Anuj& Santos, Edgardo S.. 2011. Systemic Lupus Erythematosus Presenting as Thrombotic Thrombocytopenia Purpura : How Close Is Close Enough?. Case Reports in Medicine،Vol. 2011, no. 2011, pp.1-3.
https://search.emarefa.net/detail/BIM-458838
Modern Language Association (MLA)
Perez, Cesar A.…[et al.]. Systemic Lupus Erythematosus Presenting as Thrombotic Thrombocytopenia Purpura : How Close Is Close Enough?. Case Reports in Medicine No. 2011 (2011), pp.1-3.
https://search.emarefa.net/detail/BIM-458838
American Medical Association (AMA)
Perez, Cesar A.& Abdo, Nabil& Shrestha, Anuj& Santos, Edgardo S.. Systemic Lupus Erythematosus Presenting as Thrombotic Thrombocytopenia Purpura : How Close Is Close Enough?. Case Reports in Medicine. 2011. Vol. 2011, no. 2011, pp.1-3.
https://search.emarefa.net/detail/BIM-458838
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458838