Triamcinolone and Bevacizumab as Adjunctive Therapies to Panretinal Photocoagulation for Proliferative Diabetic Retinopathy
Joint Authors
Gómez-Ulla, Francisco
Rodriguez-Cid, M. J.
Lopez-Lopez, F.
Arias, L.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-22
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Purpose.
To evaluate efficacy of intravitreal triamcinolone (IVT) and bevacizumab (IVB) as adjunctive treatments to panretinal photocoagulation (PRP) in proliferative diabetic retinopathy (PDR).
Methods.
In 60 eyes of 45 patients with PDR, PRP (PRP group), PRP with IVT (IVT group), or PRP with IVB (IVB group) was performed.
Regression of new vessels (NV), changes in best-corrected visual acuity (BCVA), central macular thickness (CMT), and contrast sensitivity at 1,2, and 6 months were evaluated.
Results.
Initial mean numbers of active NV and BCVA were 3.45 and 67.35 in the PRP group, 4.35 and 76.65 in the IVT group, and 4.79 and 75.53 in the IVB group.
At the 6-month follow-up, numbers of active NV were 2.5 (P=0.064), 1.11 (P=0.000), and 1.11 (P=0.002), and there was a mean loss of 2,6 (P=0.055), 3.9 (P=0.011), and 0.9 letters (P=0.628) in the PRP, IVT, and IVB groups, respectively.
Changes in CMT in the PRP and IVT groups were not significant, but significantly increased in the IVB group (P=0.032).
Contrast sensitivity remained stable in PRP and IVB groups and slightly decreased in IVT group.
Conclusions.
Adjunctive use of both triamcinolone and bevacizumab with PRP lead to a greater reduction of active NV than PRP alone in PDR, although no differences were seen between the two of them.
American Psychological Association (APA)
Lopez-Lopez, F.& Gómez-Ulla, Francisco& Rodriguez-Cid, M. J.& Arias, L.. 2012. Triamcinolone and Bevacizumab as Adjunctive Therapies to Panretinal Photocoagulation for Proliferative Diabetic Retinopathy. ISRN Ophthalmology،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-458855
Modern Language Association (MLA)
Lopez-Lopez, F.…[et al.]. Triamcinolone and Bevacizumab as Adjunctive Therapies to Panretinal Photocoagulation for Proliferative Diabetic Retinopathy. ISRN Ophthalmology No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-458855
American Medical Association (AMA)
Lopez-Lopez, F.& Gómez-Ulla, Francisco& Rodriguez-Cid, M. J.& Arias, L.. Triamcinolone and Bevacizumab as Adjunctive Therapies to Panretinal Photocoagulation for Proliferative Diabetic Retinopathy. ISRN Ophthalmology. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-458855
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458855