HIV Mother-to-Child Transmission, Mode of Delivery, and Duration of Rupture of Membranes : Experience in the Current Era
Joint Authors
Bitnun, Ari
Mark, Siobhan
Murphy, Kellie E.
Yudin, Mark H.
Read, Stanley
Source
Infectious Diseases in Obstetrics and Gynecology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-28
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
To evaluate whether the length of time of rupture of membranes (ROM) in optimally managed HIV-positive women on highly active antiretroviral therapy (HAART) with low viral loads (VL) is predictive of the risk of mother to child transmission (MTCT) of the human immunodeficiency virus (HIV).
Study Methods.
A retrospective case series of all HIV-positive women who delivered at two academic tertiary centers in Toronto, Canada from January 2000 to November 2010 was completed.
Results.
Two hundred and ten HIV-positive women with viral loads <1,000 copies/ml delivered during the study period.
VL was undetectable (<50 copies/mL) for the majority of the women (167, 80%), and <1,000 copies/mL for all women.
Mode of delivery was vaginal in 107 (51%) and cesarean in 103 (49%).
The median length of time of ROM was 0.63 hours (range 0 to 77.87 hours) for the entire group and 2.56 hours (range 0 to 53.90 hours) for those who had a vaginal birth.
Among women with undetectable VL, 90 (54%) had a vaginal birth and 77 (46%) had a cesarean birth.
Among the women in this cohort there were no cases of MTCT of HIV.
Conclusions.
There was no association between duration of ROM or mode of delivery and MTCT in this cohort of 210 virally suppressed HIV-positive pregnant women.
American Psychological Association (APA)
Mark, Siobhan& Murphy, Kellie E.& Read, Stanley& Bitnun, Ari& Yudin, Mark H.. 2012. HIV Mother-to-Child Transmission, Mode of Delivery, and Duration of Rupture of Membranes : Experience in the Current Era. Infectious Diseases in Obstetrics and Gynecology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-458880
Modern Language Association (MLA)
Mark, Siobhan…[et al.]. HIV Mother-to-Child Transmission, Mode of Delivery, and Duration of Rupture of Membranes : Experience in the Current Era. Infectious Diseases in Obstetrics and Gynecology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-458880
American Medical Association (AMA)
Mark, Siobhan& Murphy, Kellie E.& Read, Stanley& Bitnun, Ari& Yudin, Mark H.. HIV Mother-to-Child Transmission, Mode of Delivery, and Duration of Rupture of Membranes : Experience in the Current Era. Infectious Diseases in Obstetrics and Gynecology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-458880
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458880