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Impact of Cardiac Computed Tomographic Angiography Findings on Planning of Cancer Therapy in Patients with Concomitant Structural Heart Disease
Joint Authors
Mouhayar, Elie
Gladish, Gregory
Yusuf, Syed Wamique
Banchs, Jose
Daher, Iyad N.
Durand, Jean-Bernard
Source
Cardiology Research and Practice
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-04-04
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Exclusion of underlying coronary artery disease (CAD) is essential in the diagnosis of chemotherapy-induced cardiomyopathy.
Presence and severity of CAD can also impact the choice of therapy in cancer patients.
The value of cardiac computed tomographic angiography (CCTA) in this setting has not been reported.
Methods.
We collected data on the clinical presentation and indications for CCTA performed from January to December 2008 at the University of Texas MD Anderson Cancer Center (MDACC).
All examinations were performed using a 64-detector scanner.
CCTA results and subsequent treatment decisions were examined.
Results.
A total of 80 patients underwent CCTA during the study period for the following indications (not mutually exclusive): cardiomyopathy of unknown etiology in 33 pts (41.3%), chest pain in 32 (40.0%), abnormal stress test in 16 (20.0%), abnormal cardiac markers in 8 (10.0%), suspected cardiac mass or thrombus in 7 (8.8%).
Chemotherapy-induced cardiomyopathy was diagnosed in 18 pts (22.5%).
Severe CAD was detected in 22 pts (27.5%); due to concomitant advanced cancer or patient refusal, only 12 underwent coronary angiogram.
Of these, 4 pts (5% of total) underwent coronary artery bypass grafting.
A total of 41 pts (51.3%) had their cancer management altered based on CCTA findings.
Conclusion.
CCTA is useful in evaluating cancer pts with structural heart disease and can have an impact on the management of cancer and cardiac disease.
American Psychological Association (APA)
Daher, Iyad N.& Banchs, Jose& Yusuf, Syed Wamique& Mouhayar, Elie& Durand, Jean-Bernard& Gladish, Gregory. 2011. Impact of Cardiac Computed Tomographic Angiography Findings on Planning of Cancer Therapy in Patients with Concomitant Structural Heart Disease. Cardiology Research and Practice،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-458886
Modern Language Association (MLA)
Daher, Iyad N.…[et al.]. Impact of Cardiac Computed Tomographic Angiography Findings on Planning of Cancer Therapy in Patients with Concomitant Structural Heart Disease. Cardiology Research and Practice No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-458886
American Medical Association (AMA)
Daher, Iyad N.& Banchs, Jose& Yusuf, Syed Wamique& Mouhayar, Elie& Durand, Jean-Bernard& Gladish, Gregory. Impact of Cardiac Computed Tomographic Angiography Findings on Planning of Cancer Therapy in Patients with Concomitant Structural Heart Disease. Cardiology Research and Practice. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-458886
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458886