An Innocent Appearing Subcutaneous Nodule Diagnoses a Small Cell Lung Cancer in a Never-Smoker Female
Joint Authors
Niazi, Masooma
Duncalf, Richard
Sinha, Nupur
Diaz-Fuentes, Gilda
Source
Case Reports in Oncological Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-10
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Lung cancer among never-smokers is recognized as the 7th most common cause of cancer death globally.
Adenocarcinoma is the most commonly reported histology.
Small cell lung cancer (SCLC) has the strongest association with smoking and is rarely reported in never-smokers.
Although lung cancer in never-smokers is more common in women, the overall incidence of SCLC in female never-smokers still remains low.
Soft tissue metastases from any cancer are rare with an overall prevalence of 1.8%.
Soft tissue metastases from lung primary are uncommon, mostly from adenocarcinoma, and portend a poor prognosis.
Cutaneous metastases from SCLC are exceptionally rare with reported incidence of 0.3% to 0.8%.
We believe ours is the first reported case of SCLC presenting as subcutaneous nodule, in a never-smoker, otherwise asymptomatic female.
The diagnosis of SCLC was made incidentally by the excisional biopsy of the subcutaneous nodule.
Subsequent CT chest and PET scan revealed a hypermetabolic right lower lobe spiculated lung mass with adrenal and liver involvement.
Platinum and etoposide chemotherapy with prophylactic cranial irradiation was initiated for advanced SCLC, and she required further irinotecan and taxol for subsequent pancreatic and adrenal metastases.
With continued deterioration, she died approximately 36 months from diagnosis, while under hospice care.
American Psychological Association (APA)
Sinha, Nupur& Niazi, Masooma& Diaz-Fuentes, Gilda& Duncalf, Richard. 2014. An Innocent Appearing Subcutaneous Nodule Diagnoses a Small Cell Lung Cancer in a Never-Smoker Female. Case Reports in Oncological Medicine،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-458914
Modern Language Association (MLA)
Sinha, Nupur…[et al.]. An Innocent Appearing Subcutaneous Nodule Diagnoses a Small Cell Lung Cancer in a Never-Smoker Female. Case Reports in Oncological Medicine No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-458914
American Medical Association (AMA)
Sinha, Nupur& Niazi, Masooma& Diaz-Fuentes, Gilda& Duncalf, Richard. An Innocent Appearing Subcutaneous Nodule Diagnoses a Small Cell Lung Cancer in a Never-Smoker Female. Case Reports in Oncological Medicine. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-458914
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458914