Ankylosing Spondylitis Patients Commencing Biologic Therapy Have High Baseline Levels of Comorbidity : A Report from the Australian Rheumatology Association Database
Source
International Journal of Rheumatology
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-08-02
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Aims.
To compare the baseline characteristics of a population-based cohort of patients with ankylosing spondylitis (AS) commencing biological therapy to the reported characteristics of bDMARD randomised controlled trials (RCTs) participants.
Methods.
Descriptive analysis of AS participants in the Australian Rheumatology Association Database (ARAD) who were commencing bDMARD therapy.
Results.
Up to December 2008, 389 patients with AS were enrolled in ARAD.
354 (91.0%) had taken bDMARDs at some time, and 198 (55.9%) completed their entry questionnaire prior to or within 6 months of commencing bDMARDs.
131 (66.1%) had at least one comorbid condition, and 24 (6.8%) had a previous malignancy (15 nonmelanoma skin, 4 melanoma, 2 prostate, 1 breast, cervix, and bowel).
Compared with RCT participants, ARAD participants were older, had longer disease duration and higher baseline disease activity.
Conclusions.
AS patients commencing bDMARDs in routine care are significantly different to RCT participants and have significant baseline comorbidities.
American Psychological Association (APA)
2009. Ankylosing Spondylitis Patients Commencing Biologic Therapy Have High Baseline Levels of Comorbidity : A Report from the Australian Rheumatology Association Database. International Journal of Rheumatology،Vol. 2009, no. 2009, pp.1-10.
https://search.emarefa.net/detail/BIM-458933
Modern Language Association (MLA)
Ankylosing Spondylitis Patients Commencing Biologic Therapy Have High Baseline Levels of Comorbidity : A Report from the Australian Rheumatology Association Database. International Journal of Rheumatology No. 2009 (2009), pp.1-10.
https://search.emarefa.net/detail/BIM-458933
American Medical Association (AMA)
Ankylosing Spondylitis Patients Commencing Biologic Therapy Have High Baseline Levels of Comorbidity : A Report from the Australian Rheumatology Association Database. International Journal of Rheumatology. 2009. Vol. 2009, no. 2009, pp.1-10.
https://search.emarefa.net/detail/BIM-458933
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458933