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Stripping Voltammetric Determination of Analgesics in Their Pharmaceuticals Using Nano-Riboflavin-Modified Glassy Carbon Electrode
Joint Authors
Muralidharan, Baladhandapani
Vedhi, Chinnapiyan
Manisankar, Paramasivam
Gopu, Gopalakrishnan
Source
International Journal of Electrochemistry
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-23
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Cyclic voltammetric behaviors of three analgesics, acetaminophen (AAP), acetylsalicylic acid (ASA), and dipyrone (DP), were studied using nano-riboflavin-modified glassy carbon electrode.
One well-defined oxidation peak each for AAP and ASA and three oxidation peaks for DP were observed.
The influence of pH, scan rate, and concentration reveals irreversible diffusion controlled reaction.
The SEM analysis confirmed good accumulation of the drugs on the electrode surface.
Calibration was made under the maximum peak current conditions.
The concentration range studied for the determination of drugs was 0.02 to 0.4 μg mL−1 for AAP and ASA and 0.025 to 0.4 μg mL−1 for DP.
The lower limit of detection observed for AAP, ASA, and DP was 0.016, 0.007 μg mL−1, and 0.013 μg mL−1, respectively.
The suitability of the method for the determination of these analgesics in pharmaceutical preparations and urine samples was also ascertained.
American Psychological Association (APA)
Gopu, Gopalakrishnan& Manisankar, Paramasivam& Muralidharan, Baladhandapani& Vedhi, Chinnapiyan. 2011. Stripping Voltammetric Determination of Analgesics in Their Pharmaceuticals Using Nano-Riboflavin-Modified Glassy Carbon Electrode. International Journal of Electrochemistry،Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-459020
Modern Language Association (MLA)
Gopu, Gopalakrishnan…[et al.]. Stripping Voltammetric Determination of Analgesics in Their Pharmaceuticals Using Nano-Riboflavin-Modified Glassy Carbon Electrode. International Journal of Electrochemistry No. 2011 (2011), pp.1-11.
https://search.emarefa.net/detail/BIM-459020
American Medical Association (AMA)
Gopu, Gopalakrishnan& Manisankar, Paramasivam& Muralidharan, Baladhandapani& Vedhi, Chinnapiyan. Stripping Voltammetric Determination of Analgesics in Their Pharmaceuticals Using Nano-Riboflavin-Modified Glassy Carbon Electrode. International Journal of Electrochemistry. 2011. Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-459020
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459020