Comparison of Oral Zinc Sulfate with Systemic Meglumine Antimoniate in the Treatment of Cutaneous Leishmaniasis
Joint Authors
Yazdanpanah, Mohamad Javad
Tavakoli Rodi, Iman
Famili, Sororozaman
Banihashemi, Mahnaz
Yousefzadeh, Hadis
Pezeshkpoor, Fakhrozaman
Khajedaluee, Mohammad
Source
Dermatology Research and Practice
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-06
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The purpose of this study was to investigate comparison between oral zinc sulfate and meglumine antimoniate in the treatment of cutaneous leishmaniasis (CL).
So 100 patients with CL were included and randomly divided into two groups.
The first group was treated with oral zinc sulfate (10 mg/kg/day during 45 days period), and the second group was treated with systemic meglumine antimoniate (20 mg/kg/day intramuscularly for 20 days).
Acceptable cure after completing 45 days of followup occurred in 30.2% of lesions in first group, while this was 35.5% for the second group.
There is not any significant difference between the two treatment groups (P=0.42).
Serious side effects resulting in treatment discounting occurred in only meglumine antimoniate group.
Although cure rate of systemic meglumine antimoniate group was better the treatment with zinc sulfate is much easier, cheaper, more convenient in consumption, safer, and nearly close cure percentage to systemic meglumine antimoniate injections without serious side effect.
American Psychological Association (APA)
Yazdanpanah, Mohamad Javad& Banihashemi, Mahnaz& Pezeshkpoor, Fakhrozaman& Khajedaluee, Mohammad& Famili, Sororozaman& Tavakoli Rodi, Iman…[et al.]. 2011. Comparison of Oral Zinc Sulfate with Systemic Meglumine Antimoniate in the Treatment of Cutaneous Leishmaniasis. Dermatology Research and Practice،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-459030
Modern Language Association (MLA)
Yazdanpanah, Mohamad Javad…[et al.]. Comparison of Oral Zinc Sulfate with Systemic Meglumine Antimoniate in the Treatment of Cutaneous Leishmaniasis. Dermatology Research and Practice No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-459030
American Medical Association (AMA)
Yazdanpanah, Mohamad Javad& Banihashemi, Mahnaz& Pezeshkpoor, Fakhrozaman& Khajedaluee, Mohammad& Famili, Sororozaman& Tavakoli Rodi, Iman…[et al.]. Comparison of Oral Zinc Sulfate with Systemic Meglumine Antimoniate in the Treatment of Cutaneous Leishmaniasis. Dermatology Research and Practice. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-459030
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459030