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Intrauterine Growth Retardation and Nonalcoholic Fatty Liver Disease in Children
Joint Authors
Nobili, Valerio
Agostoni, Carlo
Alisi, Anna
Panera, Nadia
Source
International Journal of Endocrinology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-30
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Intrauterine growth retardation (IUGR), the most important cause of perinatal mortality and morbidity, is defined as a foetal growth less than normal for the population, often used as synonym of small for gestational age (SGA).
Studies demonstrated the relationships between metabolic syndrome (MS) and birthweight.
This study suggested that, in children, adolescents, and adults born SGA, insulin resistance could lead to other metabolic disorders: type 2 diabetes (DM2), dyslipidemia, and nonalcoholic fatty liver disease (NAFLD).
NAFLD may evolve to nonalcoholic steatohepatitis (NASH), and it is related to the development of MS.
Lifestyle intervention, physical activity, and weight reduction represent the mainstay of NAFLD therapy.
In particular, a catch-up growth reduction could decrease the risk to develop MS and NAFLD.
In this paper, we outline clinical and experimental evidences of the association between IUGR, metabolic syndrome, insulin resistance, and NAFLD and discuss on a possible management to avoid the risk of MS in adulthood.
American Psychological Association (APA)
Alisi, Anna& Panera, Nadia& Agostoni, Carlo& Nobili, Valerio. 2011. Intrauterine Growth Retardation and Nonalcoholic Fatty Liver Disease in Children. International Journal of Endocrinology،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-459066
Modern Language Association (MLA)
Alisi, Anna…[et al.]. Intrauterine Growth Retardation and Nonalcoholic Fatty Liver Disease in Children. International Journal of Endocrinology No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-459066
American Medical Association (AMA)
Alisi, Anna& Panera, Nadia& Agostoni, Carlo& Nobili, Valerio. Intrauterine Growth Retardation and Nonalcoholic Fatty Liver Disease in Children. International Journal of Endocrinology. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-459066
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459066