An Evaluation of the Diagnostic Accuracy of the Grade of Preoperative Biopsy Compared to Surgical Excision in Chondrosarcoma of the Long Bones
Joint Authors
Saifuddin, Asif
Riley, Nicholas
Rose, Barry
Rossi, Roberto
Jennings, Robert
Briggs, Timothy W. R.
Pollock, Rob
Skinner, John A.
Cannon, Steven R.
Source
International Journal of Surgical Oncology
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-04-18
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Chondrosarcoma is the second most common primary malignant bone tumour.
Distinguishing between grades is not necessarily straightforward and may alter the disease management.
We evaluated the correlation between histological grading of the preoperative image-guided needle biopsy and the resection specimen of 78 consecutive cases of chondrosarcoma of the femur, humerus, and tibia.
In 11 instances, there was a discrepancy in histological grade between the biopsy and surgical specimen.
Therefore, there was an 85.9% (67/78) accuracy rate for pre-operative histological grading of chondrosarcoma, based on needle biopsy.
However, the accuracy of the diagnostic biopsy to distinguish low-grade from high-grade chondrosarcoma was 93.6% (73/78).
We conclude that accurate image-guided biopsy is a very useful adjunct in determining histological grade of chondrosarcoma and the subsequent treatment plan.
At present, a multidisciplinary approach, comprising experienced orthopaedic surgeons, radiologists, and pathologists, offers the most reliable means of accurately diagnosing and grading of chondrosarcoma of long bones.
American Psychological Association (APA)
Jennings, Robert& Riley, Nicholas& Rose, Barry& Rossi, Roberto& Skinner, John A.& Cannon, Steven R.…[et al.]. 2010. An Evaluation of the Diagnostic Accuracy of the Grade of Preoperative Biopsy Compared to Surgical Excision in Chondrosarcoma of the Long Bones. International Journal of Surgical Oncology،Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-459077
Modern Language Association (MLA)
Jennings, Robert…[et al.]. An Evaluation of the Diagnostic Accuracy of the Grade of Preoperative Biopsy Compared to Surgical Excision in Chondrosarcoma of the Long Bones. International Journal of Surgical Oncology No. 2010 (2010), pp.1-4.
https://search.emarefa.net/detail/BIM-459077
American Medical Association (AMA)
Jennings, Robert& Riley, Nicholas& Rose, Barry& Rossi, Roberto& Skinner, John A.& Cannon, Steven R.…[et al.]. An Evaluation of the Diagnostic Accuracy of the Grade of Preoperative Biopsy Compared to Surgical Excision in Chondrosarcoma of the Long Bones. International Journal of Surgical Oncology. 2010. Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-459077
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459077