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Effect of Ageing on Systemic Inflammatory Response in Acute Pancreatitis
Joint Authors
Jancar, Sonia
Coelho, Ana Maria Mendonça
Carneiro D’Albuquerque, Luiz Augusto
Machado, Marcel Cerqueira Cesar
Source
International Journal of Inflammation
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-15
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Elderly patients show increased incidence of multiple organ dysfunction in acute pancreatitis possibly due to bacterial translocation.
This is associated with increased susceptibility to infections in older people.
Several reports have related this increased susceptibility to a proinflammatory status called inflammaging, which decreases the capacity of the immunological system to respond to antigens.
Cellular senescence also contributes to this low-grade chronic inflammation in older subjects.
We discuss here the effect of ageing on systemic inflammation, focusing on that induced by acute pancreatitis and some of the mechanisms involved.
It is important to understand the immunological changes in the elderly to adjust treatment strategies in order to reduce the morbidity and mortality associated with acute pancreatitis and other conditions that lead to systemic inflammation.
American Psychological Association (APA)
Machado, Marcel Cerqueira Cesar& Coelho, Ana Maria Mendonça& Carneiro D’Albuquerque, Luiz Augusto& Jancar, Sonia. 2012. Effect of Ageing on Systemic Inflammatory Response in Acute Pancreatitis. International Journal of Inflammation،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-459083
Modern Language Association (MLA)
Machado, Marcel Cerqueira Cesar…[et al.]. Effect of Ageing on Systemic Inflammatory Response in Acute Pancreatitis. International Journal of Inflammation No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-459083
American Medical Association (AMA)
Machado, Marcel Cerqueira Cesar& Coelho, Ana Maria Mendonça& Carneiro D’Albuquerque, Luiz Augusto& Jancar, Sonia. Effect of Ageing on Systemic Inflammatory Response in Acute Pancreatitis. International Journal of Inflammation. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-459083
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459083