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Obesity Hypertension : The Regulatory Role of Leptin
Joint Authors
Liu, Kan
Villarreal, Daniel
Salah, Ali
Szombathy, Tamas
Spear, Robert M.
Kshatriya, Shilpa
Freeman, Ronald H.
Reams, Garry P.
Source
International Journal of Hypertension
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-01-03
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Leptin is a 16-kDa-peptide hormone that is primarily synthesized and secreted by adipose tissue.
One of the major actions of this hormone is the control of energy balance by binding to receptors in the hypothalamus, leading to reduction in food intake and elevation in temperature and energy expenditure.
In addition, increasing evidence suggests that leptin, through both direct and indirect mechanisms, may play an important role in cardiovascular and renal regulation.
While the relevance of endogenous leptin needs further clarification, it appears to function as a pressure and volume-regulating factor under conditions of health.
However, in abnormal situations characterized by chronic hyperleptinemia such as obesity, it may function pathophysiologically for the development of hypertension and possibly also for direct renal, vascular, and cardiac damage.
American Psychological Association (APA)
Kshatriya, Shilpa& Liu, Kan& Salah, Ali& Szombathy, Tamas& Freeman, Ronald H.& Reams, Garry P.…[et al.]. 2011. Obesity Hypertension : The Regulatory Role of Leptin. International Journal of Hypertension،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-459124
Modern Language Association (MLA)
Kshatriya, Shilpa…[et al.]. Obesity Hypertension : The Regulatory Role of Leptin. International Journal of Hypertension No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-459124
American Medical Association (AMA)
Kshatriya, Shilpa& Liu, Kan& Salah, Ali& Szombathy, Tamas& Freeman, Ronald H.& Reams, Garry P.…[et al.]. Obesity Hypertension : The Regulatory Role of Leptin. International Journal of Hypertension. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-459124
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459124