Short Hypoxia Does not Affect Plasma Leptin in Healthy Men under Euglycemic Clamp Conditions
Joint Authors
Voss, Michaela
Schmoller, Andre
Rudolf, Sebastian
Oltmanns, Kerstin M.
Gehring, Hartmut
Schultes, Bernd
Schweiger, Ulrich
Source
International Journal of Endocrinology
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-06-01
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Leptin is involved in the endocrine control of energy expenditure and body weight regulation.
Previous studies emphasize a relationship between hypoxic states and leptin concentrations.
The aim of this study was to investigate the effects of acute hypoxia on leptin concentrations in healthy subjects.
We examined 14 healthy men.
Hypoxic conditions were induced by decreasing oxygen saturation to 75% for 30 minutes.
Plasma leptin concentrations were determined at baseline, after 3 hours of euglycemic clamping, during hypoxia, and repeatedly the following 2.5 hours thereafter.
Our results show an increase of plasma leptin concentrations in the course of 6 hours of hyperinsulinemic-euglycemic clamping which may reflect diurnal rhythmicity.
Notwithstanding, there was no difference between levels of leptin in the hypoxic and the normoxic condition (P=.2).
Since we did not find any significant changes in leptin responses upon hypoxia, plasma leptin levels do not seem to be affected by short hypoxic episodes of moderate degree.
American Psychological Association (APA)
Schmoller, Andre& Voss, Michaela& Gehring, Hartmut& Rudolf, Sebastian& Schweiger, Ulrich& Schultes, Bernd…[et al.]. 2009. Short Hypoxia Does not Affect Plasma Leptin in Healthy Men under Euglycemic Clamp Conditions. International Journal of Endocrinology،Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-459135
Modern Language Association (MLA)
Schmoller, Andre…[et al.]. Short Hypoxia Does not Affect Plasma Leptin in Healthy Men under Euglycemic Clamp Conditions. International Journal of Endocrinology No. 2009 (2009), pp.1-6.
https://search.emarefa.net/detail/BIM-459135
American Medical Association (AMA)
Schmoller, Andre& Voss, Michaela& Gehring, Hartmut& Rudolf, Sebastian& Schweiger, Ulrich& Schultes, Bernd…[et al.]. Short Hypoxia Does not Affect Plasma Leptin in Healthy Men under Euglycemic Clamp Conditions. International Journal of Endocrinology. 2009. Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-459135
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459135