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Impact of Benign Prostatic Hyperplasia Pharmacological Treatment on Transrectal Prostate Biopsy Adverse Effects
Joint Authors
Moretti, Tomás Bernardo Costa
Amstalden Neto, Arnaldo
Zamuner, Marina
Magna, Luis Alberto
Denardi, Fernandes
Reis, Leonardo Oliveira
Falcone, Ciro Eduardo
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-28
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Benign prostatic hyperplasia (BPH) pharmacological treatment may promote a decrease in prostate vascularization and bladder neck relaxation with theoretical improvement in prostate biopsy morbidity, though never explored in the literature.
Methods.
Among 242 consecutive unselected patients who underwent prostate biopsy, after excluding those with history of prostate biopsy/surgery or using medications not for BPH, we studied 190 patients.
On the 15th day after procedure patients were questioned about symptoms lasting over a week and classified according to pharmacological BPH treatment.
Results.
Thirty-three patients (17%) were using alpha-blocker exclusively, five (3%) 5-alpha-reductase inhibitor exclusively, twelve (6%) patients used both medications, and 140 (74%) patients used none.
There was no difference in regard to age among groups (P=0.5).
Postbiopsy adverse effects occurred as follows: hematuria 96 (50%), hematospermia 53 (28%), hematochezia 22 (12%), urethrorrhagia 19 (10%), fever 5 (3%), and pain 20 (10%).
There was a significant negative correlation between postbiopsy hematuria and BPH pharmacological treatment with stronger correlation for combined use of 5-alpha-reductase inhibitor and alpha-blocker over 6 months (P=0.0027).
Conclusion.
BPH pharmacological treatment, mainly combined for at least 6 months seems to protect against prostate biopsy adverse effects.
Future studies are necessary to confirm our novel results.
American Psychological Association (APA)
Zamuner, Marina& Falcone, Ciro Eduardo& Amstalden Neto, Arnaldo& Moretti, Tomás Bernardo Costa& Magna, Luis Alberto& Denardi, Fernandes…[et al.]. 2014. Impact of Benign Prostatic Hyperplasia Pharmacological Treatment on Transrectal Prostate Biopsy Adverse Effects. Advances in Urology،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-459179
Modern Language Association (MLA)
Zamuner, Marina…[et al.]. Impact of Benign Prostatic Hyperplasia Pharmacological Treatment on Transrectal Prostate Biopsy Adverse Effects. Advances in Urology No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-459179
American Medical Association (AMA)
Zamuner, Marina& Falcone, Ciro Eduardo& Amstalden Neto, Arnaldo& Moretti, Tomás Bernardo Costa& Magna, Luis Alberto& Denardi, Fernandes…[et al.]. Impact of Benign Prostatic Hyperplasia Pharmacological Treatment on Transrectal Prostate Biopsy Adverse Effects. Advances in Urology. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-459179
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459179