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Exhaled Nitric Oxide as a Biomarker in COPD and Related Comorbidities
Joint Authors
Ragnoli, Beatrice
Olivini, Alessia
Montuschi, Paolo
Radaeli, Alessandro
Malerba, Mario
Damiani, Giovanni
Ricciardolo, Fabio L. M.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-27
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Chronic Obstructive Pulmonary Disease (COPD) is defined as a disease characterized by persistent, progressive airflow limitation.
Recent studies have underlined that COPD is correlated to many systemic manifestations, probably due to an underlying pattern of systemic inflammation.
In COPD fractional exhaled Nitric Oxide (FeNO) levels are related to smoking habits and disease severity, showing a positive relationship with respiratory functional parameters.
Moreover FeNO is increased in patients with COPD exacerbation, compared with stable ones.
In alpha-1 antitrypsin deficiency, a possible cause of COPD, FeNO levels may be monitored to early detect a disease progression.
FeNO measurements may be useful in clinical setting to identify the level of airway inflammation, per se and in relation to comorbidities, such as pulmonary arterial hypertension and cardiovascular diseases, either in basal conditions or during treatment.
Finally, some systemic inflammatory diseases, such as psoriasis, have been associated with higher FeNO levels and potentially with an increased risk of developing COPD.
In these systemic inflammatory diseases, FeNO monitoring may be a useful biomarker for early diagnosis of COPD development.
American Psychological Association (APA)
Malerba, Mario& Radaeli, Alessandro& Olivini, Alessia& Damiani, Giovanni& Ragnoli, Beatrice& Montuschi, Paolo…[et al.]. 2014. Exhaled Nitric Oxide as a Biomarker in COPD and Related Comorbidities. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-459243
Modern Language Association (MLA)
Malerba, Mario…[et al.]. Exhaled Nitric Oxide as a Biomarker in COPD and Related Comorbidities. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-459243
American Medical Association (AMA)
Malerba, Mario& Radaeli, Alessandro& Olivini, Alessia& Damiani, Giovanni& Ragnoli, Beatrice& Montuschi, Paolo…[et al.]. Exhaled Nitric Oxide as a Biomarker in COPD and Related Comorbidities. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-459243
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459243