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Metabolic Syndrome, Hormone Levels, and Inflammation in Patients with Erectile Dysfunction
Joint Authors
Arias-Santiago, Salvador
López-Carmona Pintado, Fernando
Arrabal-Martin, Miguel
Zuluaga-Gómez, Armando
Merino-Salas, Sergio
Lahoz-García, Clara
Arrabal-Polo, Miguel Ángel
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Background.
The end point of this study was to investigate the prevalence of MS in patients with ED in comparison with control subjects and to analyse the association with acute phase reactants (CRP, ESR) and hormone levels.
Methods.
This case-control study included 65 patients, 37 with erectile dysfunction, according to the International Index of Erectile Function (IIEF) from the Urology Department of San Cecilio University Hospital, Granada (Spain) and 28 healthy controls.
The prevalence of metabolic syndrome was calculated according to ATP-III criteria.
Hormone levels and acute phase parameters were studied in samples drawn.
Results.
The ATP-III criteria for MS were met by 64.9% of the patients with ED and only 9.5% of the controls (P<0.0001, OR = 17.53, 95% CI: 3.52–87.37).
Binary logistic regression analysis showed a strong association between patients with ED and MS, even after additional adjustment for confounding factors (OR = 20.05, 95% CI: 1.24–32.82, P<0.034).
Patients with hypogonadism presented a significantly higher prevalence of metabolic syndrome.
Multiple linear regression analysis showed that systolic BP and CRP predicted 0.46 (model R2) of IIEF changes.
Conclusion.
Chronic inflammation found in patients with ED might explain the association between ED and metabolic syndrome.
American Psychological Association (APA)
Arrabal-Polo, Miguel Ángel& Arias-Santiago, Salvador& López-Carmona Pintado, Fernando& Merino-Salas, Sergio& Lahoz-García, Clara& Zuluaga-Gómez, Armando…[et al.]. 2012. Metabolic Syndrome, Hormone Levels, and Inflammation in Patients with Erectile Dysfunction. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-459314
Modern Language Association (MLA)
Arrabal-Polo, Miguel Ángel…[et al.]. Metabolic Syndrome, Hormone Levels, and Inflammation in Patients with Erectile Dysfunction. The Scientific World Journal No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-459314
American Medical Association (AMA)
Arrabal-Polo, Miguel Ángel& Arias-Santiago, Salvador& López-Carmona Pintado, Fernando& Merino-Salas, Sergio& Lahoz-García, Clara& Zuluaga-Gómez, Armando…[et al.]. Metabolic Syndrome, Hormone Levels, and Inflammation in Patients with Erectile Dysfunction. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-459314
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459314