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Fosfluconazole for Antifungal Prophylaxis in Very Low Birth Weight Infants
Joint Authors
Shirahata, Akira
Matsui, Miyu
Kubo, Kazuyasu
Takahashi, Daijiro
Nakamura, Tomohiko
Sato, Hiroshi
Shigematsu, Reiko
Araki, Shunsuke
Source
International Journal of Pediatrics
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-05-25
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
We conducted a retrospective case series study to evaluate the safety of fosfluconazole prophylaxis for preventing invasive fungal infection in VLBW infants with a central vascular access.
Fosfluconazole was administered intravenously at a dose of 6 mg/kg everyday during which time a central venous catheter was placed.
A total of 23 infants met the criteria for enrollment in our study.
No cases of fungal infection were detected during the central venous catheter placement in the group.
None of the infants had an elevated β-D-glucan, and all of them were still alive at discharge.
Regarding the liver and renal function, no statistically significant differences were observed before and at the end of fosfluconazole prophylaxis.
The results of this study demonstrate that fosfluconazole prophylaxis in preventing invasive fungal infection was well tolerated by VLBW infants.
This is a first report to describe antifungal prophylaxis using fosfluconazole for VLBW infants.
American Psychological Association (APA)
Takahashi, Daijiro& Nakamura, Tomohiko& Shigematsu, Reiko& Matsui, Miyu& Araki, Shunsuke& Kubo, Kazuyasu…[et al.]. 2009. Fosfluconazole for Antifungal Prophylaxis in Very Low Birth Weight Infants. International Journal of Pediatrics،Vol. 2009, no. 2009, pp.1-3.
https://search.emarefa.net/detail/BIM-459490
Modern Language Association (MLA)
Takahashi, Daijiro…[et al.]. Fosfluconazole for Antifungal Prophylaxis in Very Low Birth Weight Infants. International Journal of Pediatrics No. 2009 (2009), pp.1-3.
https://search.emarefa.net/detail/BIM-459490
American Medical Association (AMA)
Takahashi, Daijiro& Nakamura, Tomohiko& Shigematsu, Reiko& Matsui, Miyu& Araki, Shunsuke& Kubo, Kazuyasu…[et al.]. Fosfluconazole for Antifungal Prophylaxis in Very Low Birth Weight Infants. International Journal of Pediatrics. 2009. Vol. 2009, no. 2009, pp.1-3.
https://search.emarefa.net/detail/BIM-459490
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459490