Cognitive Functions and Cognitive Reserve in Relation to Blood Pressure Components in a Population-Based Cohort Aged 53 to 94 Years
Joint Authors
Palatini, Paolo
De Lazzari, Fabia
Tikhonoff, Valérie
Piccoli, Antonio
Bascelli, Anna
Boschetti, Giovanni
Casiglia, Edoardo
Giordano, Nunzia
Bisiacchi, Patrizia
Grasselli, Carla
Mazza, Alberto
Caffi, Sandro
Martini, Bortolo
Source
International Journal of Hypertension
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-04
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
In 288 men and women from general population in a cross-sectional survey, all neuropsychological tests were negatively associated with age; memory and executive function were also positively related with education.
The hypertensives (HT) were less efficient than the normotensives (NT) in the test of memory with interference at 10 sec (MI-10) (−33%, P=0.03), clock drawing test (CLOX) (−28%, P<0.01), and mini-mental state examination (MMSE) (−6%, P=0.02).
Lower MMSE, MI-10, and CLOX were predicted by higher systolic (odds ratio, OR, 0.97, P=0.02; OR 0.98, P<0.005; OR 0.95, P<0.001) and higher pulse blood pressure (BP) (OR 0.97, P=0.02; OR 0.97, P<0.01; and 0.95, P<0.0001).
The cognitive reserve index (CRI) was 6% lower in the HT (P=0.03) and was predicted by higher pulse BP (OR 0.82, P<0.001).
The BP vectors of lower MMSE, MI-10, and CLOX were directed towards higher values of systolic and diastolic BP, that of low CRI towards higher systolic and lower diastolic.
The label of hypertension and higher values of systolic or pulse BP are associated to worse memory and executive functions.
Higher diastolic BP, although insufficient to impair cognition, strengthens this association.
CRI is predicted by higher systolic BP associated to lower diastolic BP.
American Psychological Association (APA)
Giordano, Nunzia& Tikhonoff, Valérie& Palatini, Paolo& Bascelli, Anna& Boschetti, Giovanni& De Lazzari, Fabia…[et al.]. 2012. Cognitive Functions and Cognitive Reserve in Relation to Blood Pressure Components in a Population-Based Cohort Aged 53 to 94 Years. International Journal of Hypertension،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-459497
Modern Language Association (MLA)
Giordano, Nunzia…[et al.]. Cognitive Functions and Cognitive Reserve in Relation to Blood Pressure Components in a Population-Based Cohort Aged 53 to 94 Years. International Journal of Hypertension No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-459497
American Medical Association (AMA)
Giordano, Nunzia& Tikhonoff, Valérie& Palatini, Paolo& Bascelli, Anna& Boschetti, Giovanni& De Lazzari, Fabia…[et al.]. Cognitive Functions and Cognitive Reserve in Relation to Blood Pressure Components in a Population-Based Cohort Aged 53 to 94 Years. International Journal of Hypertension. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-459497
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459497