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Elevated Evolutionary Rates among Functionally Diverged Reproductive Genes across Deep Vertebrate Lineages
Joint Authors
Grassa, Christopher J.
Kulathinal, Rob J.
Source
International Journal of Evolutionary Biology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-28
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Among closely related taxa, proteins involved in reproduction generally evolve more rapidly than other proteins.
Here, we apply a functional and comparative genomics approach to compare functional divergence across a deep phylogenetic array of egg-laying and live-bearing vertebrate taxa.
We aligned and annotated a set of 4,986 1 : 1 : 1 : 1 : 1 orthologs in Anolis carolinensis (green lizard), Danio rerio (zebrafish), Xenopus tropicalis (frog), Gallus gallus (chicken), and Mus musculus (mouse) according to function using ESTs from available reproductive (including testis and ovary) and non-reproductive tissues as well as Gene Ontology.
For each species lineage, genes were further classified as tissue-specific (found in a single tissue) or tissue-expressed (found in multiple tissues).
Within independent vertebrate lineages, we generally find that gonadal-specific genes evolve at a faster rate than gonadal-expressed genes and significantly faster than non-reproductive genes.
Among the gonadal set, testis genes are generally more diverged than ovary genes.
Surprisingly, an opposite but nonsignificant pattern is found among the subset of orthologs that remained functionally conserved across all five lineages.
These contrasting evolutionary patterns found between functionally diverged and functionally conserved reproductive orthologs provide evidence for pervasive and potentially cryptic lineage-specific selective processes on ancestral reproductive systems in vertebrates.
American Psychological Association (APA)
Grassa, Christopher J.& Kulathinal, Rob J.. 2011. Elevated Evolutionary Rates among Functionally Diverged Reproductive Genes across Deep Vertebrate Lineages. International Journal of Evolutionary Biology،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-459511
Modern Language Association (MLA)
Grassa, Christopher J.& Kulathinal, Rob J.. Elevated Evolutionary Rates among Functionally Diverged Reproductive Genes across Deep Vertebrate Lineages. International Journal of Evolutionary Biology No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-459511
American Medical Association (AMA)
Grassa, Christopher J.& Kulathinal, Rob J.. Elevated Evolutionary Rates among Functionally Diverged Reproductive Genes across Deep Vertebrate Lineages. International Journal of Evolutionary Biology. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-459511
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459511