A Proposed Method for Thermal Specific Bioimaging and Therapy Technique for Diagnosis and Treatment of Malignant Tumors by Using Magnetic Nanoparticles
Joint Authors
Gescheit, Iddo M.
Ben-David, Moshe
Gannot, Israel
Source
Advances in Optical Technologies
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-06-22
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Topics
Abstract EN
The objective of this research program is to develop a novel, noninvasive, low-cost infrared (8–12 μm spectral range) imaging technique that would improve upon current methods using nanostructured core/shell magnetic/noble metal-based imaging and therapies.
The biocompatible magnetic nanoparticles are able to produce heat under AC magnetic field.
This thermal radiation propagates along the tissue by thermal conduction reaching the medium's (tissue's) surface.
The surface temperature distribution is acquired by a thermal camera and can be analyzed to retrieve and reconstruct nanoparticles' temperature and location within the tissue.
The technique may function as a diagnostic tool thanks to the ability of specific bioconjugation of these nanoparticles to tumor's outer surface markers.
Hence, by applying a magnetic field, we could cause a selective elevation of temperature of the targeted nanoparticles up to 5∘C, which detects the tumor.
Furthermore, elevating the temperature over 65∘C and up to 100∘C stimulates a thermo ablating interaction which causes a localized irreversible damage to the cancerous site with no harm to the surrounding tissue.
While functioning as a diagnostic tool, this procedure may serve as a targeted therapeutic tool under thermal feedback control as well.
American Psychological Association (APA)
Gescheit, Iddo M.& Ben-David, Moshe& Gannot, Israel. 2008. A Proposed Method for Thermal Specific Bioimaging and Therapy Technique for Diagnosis and Treatment of Malignant Tumors by Using Magnetic Nanoparticles. Advances in Optical Technologies،Vol. 2008, no. 2008, pp.1-7.
https://search.emarefa.net/detail/BIM-459524
Modern Language Association (MLA)
Gescheit, Iddo M.…[et al.]. A Proposed Method for Thermal Specific Bioimaging and Therapy Technique for Diagnosis and Treatment of Malignant Tumors by Using Magnetic Nanoparticles. Advances in Optical Technologies No. 2008 (2008), pp.1-7.
https://search.emarefa.net/detail/BIM-459524
American Medical Association (AMA)
Gescheit, Iddo M.& Ben-David, Moshe& Gannot, Israel. A Proposed Method for Thermal Specific Bioimaging and Therapy Technique for Diagnosis and Treatment of Malignant Tumors by Using Magnetic Nanoparticles. Advances in Optical Technologies. 2008. Vol. 2008, no. 2008, pp.1-7.
https://search.emarefa.net/detail/BIM-459524
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459524