Polypoid Adenomyoma of Endocervical Type

Abstract EN

We report herein a 53-year-old Japanese female case of polypoid adenomyoma of endocervical type.

A sessile 16 mm sized cervical polyp, hard in consistency, was surgically removed.

Histologically, the polypoid lesion was composed of smooth muscle bundles and scattered benign-looking endocervical glands.

The mucin was diffusely alcianophilic.

Immunohistochemically, some mucous glands were positive for MUC1 (CA15-3) and MUC5AC, and the other small glands were immunoreactive for MUC6.

MUC2 and mucin characteristic of gastric gland mucous cells (M-GGMC-1 or HIK1083) were negative.

Carcinoembryonic antigen was consistently expressed along the apical surface.

Estrogen receptor was positive, while progesterone receptor was negative.

Ki-67 labeling index was low.

These findings were consistent with the endocervical nature of the mucin-producing columnar cells.

This is the 18th case of adenomyoma of endocervical type reported in the English literature.