Novel Zinc(II) Complexes of Heterocyclic Ligands as Antimicrobial Agents : Synthesis, Characterisation, and Antimicrobial Studies
Joint Authors
Mandewale, Mustapha
Atram, R. G.
Yamgar, Ramesh S.
Nalawade, Satish
Sawant, Sudhir S.
Nivid, Y.
Source
Bioinorganic Chemistry and Applications
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-23
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Topics
Abstract EN
The synthesis and antimicrobial activity of novel Zn(II) metal complexes derived from three novel heterocyclic Schiff base ligands 8-[(Z)-{[3-(N-methylamino)propyl]imino}methyl]-7-hydroxy-4-methyl-2H-chromen-2-one, 2-[(E)-{[4-(1H-1,2,4-triazol-1-ylmethyl)phenyl]imino}methyl]phenol, and (4S)-4-{4-[(E)-(2-hydroxybenzylidene)amino]benzyl}-1,3-oxazolidin-2-one have been described.
These Schiff base ligands and metal complexes are characterised by spectroscopic techniques.
According to these data, we propose an octahedral geometry to all the metal complexes.
Antimicrobial activity of the Schiff base ligand and its metal complexes was studied against Gram negative bacteria: E.
coli and Pseudomonas fluorescens, Gram positive bacteria: Staphylococcus aureus, and also against fungi, that is, C.
albicans and A.
niger.
Some of the metal complexes show significant antifungal activity (MIC < 0.2 μg/mL).
The “in vitro” data has identified [Zn(NMAPIMHMC)2]·2H2O, [Zn(TMPIMP)2]·2H2O, and [Zn(HBABO)2]·2H2O as potential therapeutic antifungal agents against C.
albicans and A.
niger.
American Psychological Association (APA)
Yamgar, Ramesh S.& Nivid, Y.& Nalawade, Satish& Mandewale, Mustapha& Atram, R. G.& Sawant, Sudhir S.. 2014. Novel Zinc(II) Complexes of Heterocyclic Ligands as Antimicrobial Agents : Synthesis, Characterisation, and Antimicrobial Studies. Bioinorganic Chemistry and Applications،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-459667
Modern Language Association (MLA)
Yamgar, Ramesh S.…[et al.]. Novel Zinc(II) Complexes of Heterocyclic Ligands as Antimicrobial Agents : Synthesis, Characterisation, and Antimicrobial Studies. Bioinorganic Chemistry and Applications No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-459667
American Medical Association (AMA)
Yamgar, Ramesh S.& Nivid, Y.& Nalawade, Satish& Mandewale, Mustapha& Atram, R. G.& Sawant, Sudhir S.. Novel Zinc(II) Complexes of Heterocyclic Ligands as Antimicrobial Agents : Synthesis, Characterisation, and Antimicrobial Studies. Bioinorganic Chemistry and Applications. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-459667
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459667