Glycogen Synthase Kinase 3 : A Point of Integration in Alzheimer's Disease and a Therapeutic Target?
Joint Authors
Williams, Sylvain
Perry, George
Zhu, Xiongwei
Moreira, Paula I.
Mondragón-Rodríguez, Siddhartha
Source
International Journal of Alzheimer's Disease
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-14
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Glycogen synthase kinase 3 (GSK3) has been implicated in neurological disorders; therefore, it is not surprising that there has been an increased focus towards developing therapies directed to this kinase.
Unfortunately, these current therapies have not taken into consideration the physiological role of GSK3 in crucial events like synaptic plasticity.
With this in mind we will discuss the relationship of synaptic plasticity with GSK3 and tau protein and their role as potential targets for the development of therapeutic strategies.
Finally, we will provide perspectives in developing a cocktail therapy for Alzheimer's treatment.
American Psychological Association (APA)
Mondragón-Rodríguez, Siddhartha& Perry, George& Zhu, Xiongwei& Moreira, Paula I.& Williams, Sylvain. 2012. Glycogen Synthase Kinase 3 : A Point of Integration in Alzheimer's Disease and a Therapeutic Target?. International Journal of Alzheimer's Disease،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-459674
Modern Language Association (MLA)
Mondragón-Rodríguez, Siddhartha…[et al.]. Glycogen Synthase Kinase 3 : A Point of Integration in Alzheimer's Disease and a Therapeutic Target?. International Journal of Alzheimer's Disease No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-459674
American Medical Association (AMA)
Mondragón-Rodríguez, Siddhartha& Perry, George& Zhu, Xiongwei& Moreira, Paula I.& Williams, Sylvain. Glycogen Synthase Kinase 3 : A Point of Integration in Alzheimer's Disease and a Therapeutic Target?. International Journal of Alzheimer's Disease. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-459674
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459674