Molecular Mechanism and Potential Targets for Blocking HPV-Induced Lesion Development
Joint Authors
Torres-Poveda, K.
Bermúdez-Morales, V. H.
Madrid-Marina, V.
Peralta-Zaragoza, Oscar
Guzmán-Olea, E.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-19
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Persistent infection with high-risk HPV is the etiologic agent associated with the development of cervical cancer (CC) development.
However, environmental, social, epidemiological, genetic, and host factors may have a joint influence on the risk of disease progression.
Cervical lesions caused by HPV infection can be removed naturally by the host immune response and only a small percentage may progress to cancer; thus, the immune response is essential for the control of precursor lesions and CC.
We present a review of recent research on the molecular mechanisms that allow HPV-infected cells to evade immune surveillance and potential targets of molecular therapy to inhibit tumor immune escape.
American Psychological Association (APA)
Guzmán-Olea, E.& Bermúdez-Morales, V. H.& Peralta-Zaragoza, Oscar& Torres-Poveda, K.& Madrid-Marina, V.. 2011. Molecular Mechanism and Potential Targets for Blocking HPV-Induced Lesion Development. Journal of Oncology،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-459725
Modern Language Association (MLA)
Guzmán-Olea, E.…[et al.]. Molecular Mechanism and Potential Targets for Blocking HPV-Induced Lesion Development. Journal of Oncology No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-459725
American Medical Association (AMA)
Guzmán-Olea, E.& Bermúdez-Morales, V. H.& Peralta-Zaragoza, Oscar& Torres-Poveda, K.& Madrid-Marina, V.. Molecular Mechanism and Potential Targets for Blocking HPV-Induced Lesion Development. Journal of Oncology. 2011. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-459725
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459725