Leukocyte Adhesion Molecules in Diabetic Retinopathy
Joint Authors
Ishida, Susumu
Ishibashi, Tatsuro
Noda, Kousuke
Nakao, Shintaro
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Diabetes is a systemic disease that causes a number of metabolic and physiologic abnormalities.
One of the major microvascular complications of diabetes is diabetic retinopathy (DR), a leading cause of blindness in people over age 50.
The mechanisms underlying the development of DR are not fully understood; however, extensive studies have recently implicated chronic, low-grade inflammation in the pathophysiology of DR.
During inflammation leukocytes undergo sequential adhesive interactions with endothelial cells to migrate into the inflamed tissues, a process known as the “leukocyte recruitment cascade” which is orchestrated by precise adhesion molecule expression on the cell surface of leukocytes and the endothelium.
This paper summarizes the recent clinical and preclinical works on the roles of leukocyte adhesion molecules in DR.
American Psychological Association (APA)
Noda, Kousuke& Nakao, Shintaro& Ishida, Susumu& Ishibashi, Tatsuro. 2011. Leukocyte Adhesion Molecules in Diabetic Retinopathy. Journal of Ophthalmology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-459792
Modern Language Association (MLA)
Noda, Kousuke…[et al.]. Leukocyte Adhesion Molecules in Diabetic Retinopathy. Journal of Ophthalmology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-459792
American Medical Association (AMA)
Noda, Kousuke& Nakao, Shintaro& Ishida, Susumu& Ishibashi, Tatsuro. Leukocyte Adhesion Molecules in Diabetic Retinopathy. Journal of Ophthalmology. 2011. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-459792
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459792