Can High Altitude Influence Cytokines and Sleep?
Joint Authors
Rodrigues, Bruno
Tufik, Sergio
de Mello, Marco Tulio
dos Santos, Ronaldo Vagner Thomathieli
Lira, Fabio Santos
de Aquino Lemos, Valdir
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-09
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The number of persons who relocate to regions of high altitude for work, pleasure, sport, or residence increases every year.
It is known that the reduced supply of oxygen (O2) induced by acute or chronic increases in altitude stimulates the body to adapt to new metabolic challenges imposed by hypoxia.
Sleep can suffer partial fragmentation because of the exposure to high altitudes, and these changes have been described as one of the responsible factors for the many consequences at high altitudes.
We conducted a review of the literature during the period from 1987 to 2012.
This work explored the relationships among inflammation, hypoxia and sleep in the period of adaptation and examined a novel mechanism that might explain the harmful effects of altitude on sleep, involving increased Interleukin-1 beta (IL-1β), Interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) production from several tissues and cells, such as leukocytes and cells from skeletal muscle and brain.
American Psychological Association (APA)
de Aquino Lemos, Valdir& dos Santos, Ronaldo Vagner Thomathieli& Lira, Fabio Santos& Rodrigues, Bruno& Tufik, Sergio& de Mello, Marco Tulio. 2013. Can High Altitude Influence Cytokines and Sleep?. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-459819
Modern Language Association (MLA)
de Aquino Lemos, Valdir…[et al.]. Can High Altitude Influence Cytokines and Sleep?. Mediators of Inflammation No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-459819
American Medical Association (AMA)
de Aquino Lemos, Valdir& dos Santos, Ronaldo Vagner Thomathieli& Lira, Fabio Santos& Rodrigues, Bruno& Tufik, Sergio& de Mello, Marco Tulio. Can High Altitude Influence Cytokines and Sleep?. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-459819
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459819