Atopic Dermatitis and the Atopic March : What Is New?
Joint Authors
Bellini, Federica
Neri, Iria
Raone, Beatrice
Ricci, Giampaolo
Pileri, Alessandro
Patrizi, Annalisa
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-13
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
In this paper the authors review the management of atopic dermatitis (AD) and the association between AD and allergic respiratory diseases.
Data Sources.
PubMed databases, researching articles in the last 15 years.
Results.
Studies about atopic march are cross-sectional population studies at different ages.
They show that the most important predisposing factor for atopy is a decrease of the filaggrin's expression.
Conclusions.
The most modern theories seem to show that the most important factor which starts the atopic march is represented by an impaired epidermal barrier.
It causes an increase in skin permeability to allergens that could induce sensitization even in the airways.
The major predisposing factor is a primary inherited epithelial barrier defect resulting from filaggrin gene mutation, but other factors may play a role in this complex mechanism.
Further studies are needed to focus on AD treatment and preventive strategies.
American Psychological Association (APA)
Patrizi, Annalisa& Pileri, Alessandro& Bellini, Federica& Raone, Beatrice& Neri, Iria& Ricci, Giampaolo. 2011. Atopic Dermatitis and the Atopic March : What Is New?. Journal of Allergy،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-459827
Modern Language Association (MLA)
Patrizi, Annalisa…[et al.]. Atopic Dermatitis and the Atopic March : What Is New?. Journal of Allergy No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-459827
American Medical Association (AMA)
Patrizi, Annalisa& Pileri, Alessandro& Bellini, Federica& Raone, Beatrice& Neri, Iria& Ricci, Giampaolo. Atopic Dermatitis and the Atopic March : What Is New?. Journal of Allergy. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-459827
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459827