Determinants of Tuberculosis Infection among Adult HIV Positives Attending Clinical Care in Western Ethiopia : A Case-Control Study

Abstract EN

There has been a drastic rise of tuberculosis (TB) infection across the world associated with the pandemic occurrence of HIV/AIDS.

There are various determinants factors that increase the chance of TB infection among HIV positives (TB/HIV confection) that varies contextually.

This study aimed to assess the determinants of TB/HIV coinfection among adult HIV positives attending clinical care at two public health facilities in Nekemte, western Ethiopia.

Unmatched case-control study was conducted from December 26, 2011, to February 29, 2012.

Cases were 123 TB infected HIV positives, and controls were 246 non-TB infected HIV positives.

Being divorced/widowed AOR=3.02, 95% CI (1.70, 7.88), not attending formal education AOR=4.32, 95% CI (2.20, 14.15), being underweight (BMI<18.5 kg/m2) AOR=3.87, 95% CI (2.18, 6.87), having history of diabetic mellitus AOR=3.63, 95% CI (1.33, 9.94), and being in advanced WHO HIV/AIDS clinical staging AOR=2.29, 95% CI (1.32, 3.98), were determinant factors associated with TB/HIV co-infection.

Having a separate kitchen AOR=0.48, 95% CI (0.28, 0.81) showed protective role.

For most of these determinants interventions can be made at individual and institutional levels, whereas, factors like education and nutrition need societal level integrations.