Determination of Cortisol and Dehydroepiandrosterone Levels in Saliva for Screening of Periodontitis in Older Japanese Adults
Joint Authors
Awano, Shuji
Soh, Inho
Yoshida, Akihiro
Takata, Yutaka
Hamasaki, Tomoko
Ansai, Toshihiro
Sonoki, Kazuo
Takehara, Tadamichi
Ishisaka, Aiko
Source
International Journal of Dentistry
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-02-01
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Recent reports have found a positive relationship between periodontitis and the hormones cortisol and dehydroepiandrosterone (DHEA).
We investigated the associations between those levels and periodontitis in never-smokers and smokers of elderly subjects.
Subjects and Methods.
Cortisol and DHEA levels in saliva were determined in 171 subjects (85 males, 86 females), with clinical examinations including probing depth (PD) and clinical attachment loss (CAL) also performed.
Results.
Smoking had effects on cortisol and DHEA levels, and those were significantly associated with severe PD and CAL in never-smokers.
According to ROC analysis, the cutoff values of cortisol and DHEA to obtain the optimal sensitivity and specificity for detecting severe periodontitis were 2.06 ng/mL and 60.24 pg/mL, respectively, for PD, and 2.12 ng/mL and 61.78 pg/mL, respectively, for CAL.
Conclusions.
Assessment of hormone levels may be a useful screening method for periodontitis, though limited to never-smokers.
American Psychological Association (APA)
Ansai, Toshihiro& Soh, Inho& Ishisaka, Aiko& Yoshida, Akihiro& Awano, Shuji& Hamasaki, Tomoko…[et al.]. 2010. Determination of Cortisol and Dehydroepiandrosterone Levels in Saliva for Screening of Periodontitis in Older Japanese Adults. International Journal of Dentistry،Vol. 2009, no. 2009, pp.1-8.
https://search.emarefa.net/detail/BIM-459938
Modern Language Association (MLA)
Ansai, Toshihiro…[et al.]. Determination of Cortisol and Dehydroepiandrosterone Levels in Saliva for Screening of Periodontitis in Older Japanese Adults. International Journal of Dentistry No. 2009 (2009), pp.1-8.
https://search.emarefa.net/detail/BIM-459938
American Medical Association (AMA)
Ansai, Toshihiro& Soh, Inho& Ishisaka, Aiko& Yoshida, Akihiro& Awano, Shuji& Hamasaki, Tomoko…[et al.]. Determination of Cortisol and Dehydroepiandrosterone Levels in Saliva for Screening of Periodontitis in Older Japanese Adults. International Journal of Dentistry. 2010. Vol. 2009, no. 2009, pp.1-8.
https://search.emarefa.net/detail/BIM-459938
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459938