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Screening of α-Glucosidase Inhibitory Activity from Some Plants of Apocynaceae, Clusiaceae, Euphorbiaceae, and Rubiaceae
Joint Authors
Elya, Berna
Yuliastuti, Wulan
Mun'im, Abdul
Septiana, Eva Kurnia
Basah, Katrin
Bangun, Anastasia
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-07
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Diabetes mellitus (DM) is recognized as a serious global health problem that is characterized by high blood sugar levels.
Type 2 DM is more common in diabetic populations.
In this type of DM, inhibition of α-glucosidase is a useful treatment to delay the absorption of glucose after meals.
As a megabiodiversity country, Indonesia still has a lot of potential unexploited forests to be developed as a medicine source, including as the α-glucosidase inhibitor.
In this study, we determine the α-glucosidase inhibitory activity of 80% ethanol extracts of leaves and twigs of some plants from the Apocynaceae, Clusiaceae, Euphorbiaceae, and Rubiaceae.
Inhibitory activity test of the α-glucosidase was performed in vitro using spectrophotometric methods.
Compared with the control acarbose (IC50 117.20 μg/mL), thirty-seven samples of forty-five were shown to be more potent α-glucosidase inhibitors with IC50 values in the range 2.33–112.02 μg/mL.
American Psychological Association (APA)
Elya, Berna& Basah, Katrin& Mun'im, Abdul& Yuliastuti, Wulan& Bangun, Anastasia& Septiana, Eva Kurnia. 2011. Screening of α-Glucosidase Inhibitory Activity from Some Plants of Apocynaceae, Clusiaceae, Euphorbiaceae, and Rubiaceae. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-459971
Modern Language Association (MLA)
Elya, Berna…[et al.]. Screening of α-Glucosidase Inhibitory Activity from Some Plants of Apocynaceae, Clusiaceae, Euphorbiaceae, and Rubiaceae. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-459971
American Medical Association (AMA)
Elya, Berna& Basah, Katrin& Mun'im, Abdul& Yuliastuti, Wulan& Bangun, Anastasia& Septiana, Eva Kurnia. Screening of α-Glucosidase Inhibitory Activity from Some Plants of Apocynaceae, Clusiaceae, Euphorbiaceae, and Rubiaceae. Journal of Biomedicine and Biotechnology. 2011. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-459971
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459971