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Synapse Plasticity in Motor, Sensory, and Limbo-Prefrontal Cortex Areas as Measured by Degrading Axon Terminals in an Environment Model of Gerbils (Meriones unguiculatus)
Joint Authors
Witte, A. Veronica
Neufeld, Janina
Teuchert-Noodt, Gertraud
Winter, York
Grafen, Keren
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-09-28
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Still little is known about naturally occurring synaptogenesis in the adult neocortex and related impacts of epigenetic influences.
We therefore investigated (pre)synaptic plasticity in various cortices of adult rodents, visualized by secondary lysosome accumulations (LA) in remodeling axon terminals.
Twenty-two male gerbils from either enriched (ER) or impoverished rearing (IR) were used for quantification of silver-stained LA.
ER-animals showed rather low LA densities in most primary fields, whereas barrel and secondary/associative cortices exhibited higher densities and layer-specific differences.
In IR-animals, these differences were evened out or even inverted.
Basic plastic capacities might be linked with remodeling of local intrinsic circuits in the context of cortical map adaptation in both IR- and ER-animals.
Frequently described disturbances due to IR in multiple corticocortical and extracortical afferent systems, including the mesocortical dopamine projection, might have led to maladaptations in the plastic capacities of prefronto-limbic areas, as indicated by different LA densities in IR- compared with ER-animals.
American Psychological Association (APA)
Neufeld, Janina& Teuchert-Noodt, Gertraud& Grafen, Keren& Winter, York& Witte, A. Veronica. 2009. Synapse Plasticity in Motor, Sensory, and Limbo-Prefrontal Cortex Areas as Measured by Degrading Axon Terminals in an Environment Model of Gerbils (Meriones unguiculatus). Neural Plasticity،Vol. 2009, no. 2009, pp.1-14.
https://search.emarefa.net/detail/BIM-460013
Modern Language Association (MLA)
Neufeld, Janina…[et al.]. Synapse Plasticity in Motor, Sensory, and Limbo-Prefrontal Cortex Areas as Measured by Degrading Axon Terminals in an Environment Model of Gerbils (Meriones unguiculatus). Neural Plasticity No. 2009 (2009), pp.1-14.
https://search.emarefa.net/detail/BIM-460013
American Medical Association (AMA)
Neufeld, Janina& Teuchert-Noodt, Gertraud& Grafen, Keren& Winter, York& Witte, A. Veronica. Synapse Plasticity in Motor, Sensory, and Limbo-Prefrontal Cortex Areas as Measured by Degrading Axon Terminals in an Environment Model of Gerbils (Meriones unguiculatus). Neural Plasticity. 2009. Vol. 2009, no. 2009, pp.1-14.
https://search.emarefa.net/detail/BIM-460013
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-460013