![](/images/graphics-bg.png)
Microsurgical Techniques Used to Construct the Vascularized and Neurotized Tissue Engineered Bone
Joint Authors
Zhang, Zhi-Yong
Wei, Kuanhai
Fan, Jun-jun
Chen, Bin
Pei, Guo-Xian
Bi, Long
Jin, Dan
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-12
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The lack of vascularization in the tissue engineered bone results in poor survival and ossification.
Tissue engineered bone can be wrapped in the soft tissue flaps which are rich in blood supply to complete the vascularization in vivo by microsurgical technique, and the surface of the bone graft can be invaded with new vascular network.
The intrinsic vascularization can be induced via a blood vessel or an arteriovenous loop located centrally in the bone graft by microsurgical technique.
The peripheral nerve especially peptidergic nerve has effect on the bone regeneration.
The peptidergic nerve can be used to construct the neurotized tissue engineered bone by implanting the nerve fiber into the center of bone graft.
Thus, constructing a highly vascularized and neurotized tissue engineered bone according with the theory of biomimetics has become a useful method for repairing the large bone defect.
Many researchers have used the microsurgical techniques to enhance the vascularization and neurotization of tissue engineered bone and to get a better osteogenesis effect.
This review aims to summarize the microsurgical techniques mostly used to construct the vascularized and neurotized tissue engineered bone.
American Psychological Association (APA)
Fan, Jun-jun& Bi, Long& Jin, Dan& Wei, Kuanhai& Chen, Bin& Zhang, Zhi-Yong…[et al.]. 2014. Microsurgical Techniques Used to Construct the Vascularized and Neurotized Tissue Engineered Bone. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-460052
Modern Language Association (MLA)
Fan, Jun-jun…[et al.]. Microsurgical Techniques Used to Construct the Vascularized and Neurotized Tissue Engineered Bone. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-460052
American Medical Association (AMA)
Fan, Jun-jun& Bi, Long& Jin, Dan& Wei, Kuanhai& Chen, Bin& Zhang, Zhi-Yong…[et al.]. Microsurgical Techniques Used to Construct the Vascularized and Neurotized Tissue Engineered Bone. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-460052
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-460052