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Failure of Recombinant Activated Factor VII in Treatment of Diffuse Alveolar Hemorrhage due to Cryoglobulinemic Vasculitis
Joint Authors
Khoulani, Dania
Khanshour, Ammar
Yessayan, Lenar
Kuriakose, Philip
Rao, Bharat
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-09
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Diffuse alveolar hemorrhage (DAH) is a serious complication of the small vessel vasculitis syndromes and carries a high mortality.
Recombinant activated factor VII (rFVIIa) is used to treat bleeding in patients with hemophilia and antibodies to factor VIII or IX.
It is increasingly being used in life-threatening hemorrhage in a variety of other settings in which conventional therapy is unsuccessful.
Randomized controlled trials of rFVIIa in DAH are lacking.
However, several case reports have described a complete or sustained control of DAH using rFVIIa after patients failed to respond to medical treatment.
There are no case reports in the literature describing the use or the failure of rFVIIa in DAH associated with cryoglobulinemic vasculitis.
We here report the failure of rFVIIa to control DAH in a patient with CD5+ B-cell non-Hodgkin’s lymphoma and cryoglobulinemic vasculitis.
American Psychological Association (APA)
Khoulani, Dania& Rao, Bharat& Khanshour, Ammar& Kuriakose, Philip& Yessayan, Lenar. 2014. Failure of Recombinant Activated Factor VII in Treatment of Diffuse Alveolar Hemorrhage due to Cryoglobulinemic Vasculitis. Case Reports in Hematology،Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-460162
Modern Language Association (MLA)
Khoulani, Dania…[et al.]. Failure of Recombinant Activated Factor VII in Treatment of Diffuse Alveolar Hemorrhage due to Cryoglobulinemic Vasculitis. Case Reports in Hematology No. 2014 (2014), pp.1-3.
https://search.emarefa.net/detail/BIM-460162
American Medical Association (AMA)
Khoulani, Dania& Rao, Bharat& Khanshour, Ammar& Kuriakose, Philip& Yessayan, Lenar. Failure of Recombinant Activated Factor VII in Treatment of Diffuse Alveolar Hemorrhage due to Cryoglobulinemic Vasculitis. Case Reports in Hematology. 2014. Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-460162
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-460162