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Prolonged Refractory Hypotension following Combined Amlodipine and Losartan Ingestion Responsive to Metaraminol
Joint Authors
Plumb, James O. M.
de Beer, Thearina
Stewart, Craig
Eddleston, Michael
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Introduction.
Overdose with the calcium channel blocker amlodipine can cause profound hypotension that may be exacerbated by the concurrent ingestion of an angiotensin II receptor antagonist.
Best management of such overdoses is uncertain although the use of hyperinsulinaemia-euglycaemia (HIE) has been recommended.
Case report.
We report a case of mixed amlodipine and losartan overdose in a 50-year-old lady.
Severe hypotension was resistant to conventional vasopressors and high-dose insulin/euglycaemia, but did respond to a metaraminol infusion.
Conclusion.
A trial of metaraminol early in severe cases of calcium channel blocker and angiotensin II receptor antagonist toxicity may be of benefit, especially when conventional ionotropic treatment measures are failing.
American Psychological Association (APA)
Plumb, James O. M.& Stewart, Craig& Eddleston, Michael& de Beer, Thearina. 2011. Prolonged Refractory Hypotension following Combined Amlodipine and Losartan Ingestion Responsive to Metaraminol. Case Reports in Medicine،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-460211
Modern Language Association (MLA)
Plumb, James O. M.…[et al.]. Prolonged Refractory Hypotension following Combined Amlodipine and Losartan Ingestion Responsive to Metaraminol. Case Reports in Medicine No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-460211
American Medical Association (AMA)
Plumb, James O. M.& Stewart, Craig& Eddleston, Michael& de Beer, Thearina. Prolonged Refractory Hypotension following Combined Amlodipine and Losartan Ingestion Responsive to Metaraminol. Case Reports in Medicine. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-460211
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-460211