Effect of Plant Polyphenols on Adipokine Secretion from Human SGBS Adipocytes
Joint Authors
Petraki, Maria P.
Vezyraki, Patra
Derdemezis, Christos S.
Elisaf, Moses S.
Tsimihodimos, Vasilis
Tselepis, Alexandros D.
Kiortsis, Dimitrios N.
Source
Biochemistry Research International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-22
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Introduction.
Adipose tissue contributes to atherosclerosis with mechanisms related to adipokine secretion.
Polyphenols may exhibit antiatherogenic properties.
The aim of the study was to investigate the effects of three polyphenols, namely, quercetin, epigallocatechin gallate (EGCG), and resveratrol on adipokine secretion from cultured human adipocytes.
Methods.
Human SGBS adipocytes were treated with quercetin, EGCG, and resveratrol for 24 and 48 hours.
Visfatin, leptin, and adiponectin were measured in the supernatant.
Results.
Visfatin secretion was inhibited by quercetin 10 μM by 16% and 24% at 24 and 48 hours respectively.
The corresponding changes for quercetin 25 μM were 47% and 48%.
Resveratrol 25 μM reduced visfatin by 28% and 38% at 24 and 48 hours.
EGCG did not have an effect on visfatin.
None of tested polyphenols influenced leptin and adiponectin secretion.
Conclusion.
Quercetin and resveratrol significantly decreased visfatin secretion from SGBS adipocytes.
This effect may contribute to their overall antiatherogenic properties.
American Psychological Association (APA)
Derdemezis, Christos S.& Kiortsis, Dimitrios N.& Tsimihodimos, Vasilis& Petraki, Maria P.& Elisaf, Moses S.& Tselepis, Alexandros D.…[et al.]. 2011. Effect of Plant Polyphenols on Adipokine Secretion from Human SGBS Adipocytes. Biochemistry Research International،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-460387
Modern Language Association (MLA)
Elisaf, Moses S.…[et al.]. Effect of Plant Polyphenols on Adipokine Secretion from Human SGBS Adipocytes. Biochemistry Research International No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-460387
American Medical Association (AMA)
Derdemezis, Christos S.& Kiortsis, Dimitrios N.& Tsimihodimos, Vasilis& Petraki, Maria P.& Elisaf, Moses S.& Tselepis, Alexandros D.…[et al.]. Effect of Plant Polyphenols on Adipokine Secretion from Human SGBS Adipocytes. Biochemistry Research International. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-460387
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-460387