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Aged Garlic Extract Improves Adiponectin Levels in Subjects with Metabolic Syndrome : A Double-Blind, Placebo-Controlled, Randomized, Crossover Study
Joint Authors
Oubiña, Pilar
Valero-Muñoz, Maria
Gómez-Arbeláez, Diego
Camacho, Paul Anthony
de las Heras, Natalia
López-Jaramillo, Patricio
García, Ronald Gerardo
Lahera, Vicente
Rodríguez, Yudy
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-28
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Garlic (Allium sativum) has been shown to have important benefits in individuals at high cardiovascular risk.
The aim of the present study was to evaluate the effects of the administration of aged garlic extract (AGE) on the risk factors that constitute the cluster of metabolic syndrome (MS).
Methods and Design.
Double-blind, crossover, randomized, placebo-controlled clinical trial to assess the effect of 1.2 g/day of AGE (Kyolic), for 24 weeks of treatment (12 weeks of AGE and 12 weeks of placebo), on subjects with MS.
Results.
The administration of AGE increased the plasma levels of adiponectin (P=0.027).
No serious side effects associated with the intervention were reported.
Conclusion.
The present results have shown for the first time that the administration of AGE for 12 weeks increased plasma adiponectin levels in patients with MS.
This suggests that AGE might be a useful, novel, nonpharmacological therapeutic intervention to increase adiponectin and to prevent cardiovascular (CV) complications in individuals with MS.
American Psychological Association (APA)
Gómez-Arbeláez, Diego& Lahera, Vicente& Oubiña, Pilar& Valero-Muñoz, Maria& de las Heras, Natalia& Rodríguez, Yudy…[et al.]. 2013. Aged Garlic Extract Improves Adiponectin Levels in Subjects with Metabolic Syndrome : A Double-Blind, Placebo-Controlled, Randomized, Crossover Study. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-460405
Modern Language Association (MLA)
Gómez-Arbeláez, Diego…[et al.]. Aged Garlic Extract Improves Adiponectin Levels in Subjects with Metabolic Syndrome : A Double-Blind, Placebo-Controlled, Randomized, Crossover Study. Mediators of Inflammation No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-460405
American Medical Association (AMA)
Gómez-Arbeláez, Diego& Lahera, Vicente& Oubiña, Pilar& Valero-Muñoz, Maria& de las Heras, Natalia& Rodríguez, Yudy…[et al.]. Aged Garlic Extract Improves Adiponectin Levels in Subjects with Metabolic Syndrome : A Double-Blind, Placebo-Controlled, Randomized, Crossover Study. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-460405
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-460405