The eIF4F and eIFiso4F Complexes of Plants : An Evolutionary Perspective
Joint Authors
Browning, Karen S.
Patrick, Ryan M.
Source
Comparative and Functional Genomics
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-07
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Translation initiation in eukaryotes requires a number of initiation factors to recruit the assembled ribosome to mRNA.
The eIF4F complex plays a key role in initiation and is a common target point for regulation of protein synthesis.
Most work on the translation machinery of plants to date has focused on flowering plants, which have both the eIF4F complex (eIF4E and eIF4G) as well as the plant-specific eIFiso4F complex (eIFiso4E and eIFiso4G).
The increasing availability of plant genome sequence data has made it possible to trace the evolutionary history of these two complexes in plants, leading to several interesting discoveries.
eIFiso4G is conserved throughout plants, while eIFiso4E only appears with the evolution of flowering plants.
The eIF4G N-terminus, which has been difficult to annotate, appears to be well conserved throughout the plant lineage and contains two motifs of unknown function.
Comparison of eIFiso4G and eIF4G sequence data suggests conserved features unique to eIFiso4G and eIF4G proteins.
These findings have answered some questions about the evolutionary history of the two eIF4F complexes of plants, while raising new ones.
American Psychological Association (APA)
Patrick, Ryan M.& Browning, Karen S.. 2012. The eIF4F and eIFiso4F Complexes of Plants : An Evolutionary Perspective. Comparative and Functional Genomics،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-460598
Modern Language Association (MLA)
Patrick, Ryan M.& Browning, Karen S.. The eIF4F and eIFiso4F Complexes of Plants : An Evolutionary Perspective. Comparative and Functional Genomics No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-460598
American Medical Association (AMA)
Patrick, Ryan M.& Browning, Karen S.. The eIF4F and eIFiso4F Complexes of Plants : An Evolutionary Perspective. Comparative and Functional Genomics. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-460598
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-460598