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Slice-to-Volume Nonrigid Registration of Histological Sections to MR Images of the Human Brain
Joint Authors
Osechinskiy, Sergey
Kruggel, Frithjof
Source
Anatomy Research International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-12-12
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Registration of histological images to three-dimensional imaging modalities is an important step in quantitative analysis of brain structure, in architectonic mapping of the brain, and in investigation of the pathology of a brain disease.
Reconstruction of histology volume from serial sections is a well-established procedure, but it does not address registration of individual slices from sparse sections, which is the aim of the slice-to-volume approach.
This study presents a flexible framework for intensity-based slice-to-volume nonrigid registration algorithms with a geometric transformation deformation field parametrized by various classes of spline functions: thin-plate splines (TPS), Gaussian elastic body splines (GEBS), or cubic B-splines.
Algorithms are applied to cross-modality registration of histological and magnetic resonance images of the human brain.
Registration performance is evaluated across a range of optimization algorithms and intensity-based cost functions.
For a particular case of histological data, best results are obtained with a TPS three-dimensional (3D) warp, a new unconstrained optimization algorithm (NEWUOA), and a correlation-coefficient-based cost function.
American Psychological Association (APA)
Osechinskiy, Sergey& Kruggel, Frithjof. 2010. Slice-to-Volume Nonrigid Registration of Histological Sections to MR Images of the Human Brain. Anatomy Research International،Vol. 2011, no. 2011, pp.1-17.
https://search.emarefa.net/detail/BIM-460603
Modern Language Association (MLA)
Osechinskiy, Sergey& Kruggel, Frithjof. Slice-to-Volume Nonrigid Registration of Histological Sections to MR Images of the Human Brain. Anatomy Research International No. 2011 (2011), pp.1-17.
https://search.emarefa.net/detail/BIM-460603
American Medical Association (AMA)
Osechinskiy, Sergey& Kruggel, Frithjof. Slice-to-Volume Nonrigid Registration of Histological Sections to MR Images of the Human Brain. Anatomy Research International. 2010. Vol. 2011, no. 2011, pp.1-17.
https://search.emarefa.net/detail/BIM-460603
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-460603