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Clinical Analysis on Alteration of Thyroid Hormones in the Serum of Patients with Acute Ischemic Stroke
Joint Authors
Zhang, Yonghua
Meyer, Michael A.
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-08-09
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Low T3 has been associated with increased short-term mortality in intensive care unit and long-term mortality in cardiovascular disease.
The objective of this retrospective study is to investigate associations of thyroid hormone status with clinical severity and outcome in acute ischemic stroke, and whether there is association between the pituitary axis abnormality and the anterior/posterior circulation involvement.
Patients with no history of thyroid abnormality who presented first ever stroke were studied.
Total T3, T4, TSH levels, basic and clinical characteristics were collected and categorized.
Neurological impairment was assessed using NIHSS and modified Rankin Scale.
Twenty-nine patients (61%) had T3 ≤ 75 ng/dL.
Low T3 group had significant higher NIHSS compared to normal T3 group.
There was a significant negative correlation between T3 levels and NIHSS scores on admission.
A significantly smaller percentage of patients with low T3 showed favorable neurological function improvement by both NIHSS and mRS measures compared to those with normal T3.
There was no significant difference for anterior or posterior circulation involvement between low T3 and normal T3 groups.
It is suggested that low T3 is associated with worse neurological outcome.
The severity of low T3 may be a predictor of functional improvement in acute ischemic stroke.
American Psychological Association (APA)
Zhang, Yonghua& Meyer, Michael A.. 2010. Clinical Analysis on Alteration of Thyroid Hormones in the Serum of Patients with Acute Ischemic Stroke. Stroke Research and Treatment،Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-460781
Modern Language Association (MLA)
Zhang, Yonghua& Meyer, Michael A.. Clinical Analysis on Alteration of Thyroid Hormones in the Serum of Patients with Acute Ischemic Stroke. Stroke Research and Treatment No. 2010 (2010), pp.1-5.
https://search.emarefa.net/detail/BIM-460781
American Medical Association (AMA)
Zhang, Yonghua& Meyer, Michael A.. Clinical Analysis on Alteration of Thyroid Hormones in the Serum of Patients with Acute Ischemic Stroke. Stroke Research and Treatment. 2010. Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-460781
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-460781