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Restless Legs Syndrome as the Initial Presentation of Multiple Sclerosis
Joint Authors
Irkec, Ceyla
Karacay Ozkalaycı, Sebnem
Vurallı, Doga
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-19
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The restless legs syndrome (RLS) is a common central nervous system disorder.
It is characterized by complaints of unpleasant sensation in the legs occurring during periods of leg inactivity which worsen or only occur in the evening or at night and relieved partially or totally by movement.
The RLS may be idiopathic or due to secondary causes.
It is associated with several pathological or physiological conditions.
Iron metabolism and dysfunctions of the dopaminergic system are the most important factors in the pathophysiology.
There are several studies suggesting multiple sclerosis as one of the causes of symptomatic RLS.
Here, we report a case of RLS as the initial presentation of MS.
The sudden onset of RLS symptoms in our patient suggested the possibility of an underlying cause.
His diagnostic evaluation excluded other causes of RLS and his clinical course suggested that RLS was due to MS.
MS with the spinal cord involvement is mostly associated with RLS, but any lesion in the hypothalamic-spinal connection may cause disinhibition of lower spinal levels, resulting in RLS.
RLS as the initial presentation of MS reflects that the pathophysiology of RLS in MS is related to inflammatory demyelination rather than axonal degeneration.
American Psychological Association (APA)
Irkec, Ceyla& Vurallı, Doga& Karacay Ozkalaycı, Sebnem. 2013. Restless Legs Syndrome as the Initial Presentation of Multiple Sclerosis. Case Reports in Medicine،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-460790
Modern Language Association (MLA)
Irkec, Ceyla…[et al.]. Restless Legs Syndrome as the Initial Presentation of Multiple Sclerosis. Case Reports in Medicine No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-460790
American Medical Association (AMA)
Irkec, Ceyla& Vurallı, Doga& Karacay Ozkalaycı, Sebnem. Restless Legs Syndrome as the Initial Presentation of Multiple Sclerosis. Case Reports in Medicine. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-460790
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-460790