Rhenium-188 Production in Hospitals, by W-188Re-188 Generator, for Easy Use in Radionuclide Therapy
Joint Authors
Andreou, Maria
Valassi, Alexia
Lyra, Maria
Argyrou, Maria
Source
International Journal of Molecular Imaging
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-09
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Rhenium-188 (Re-188) is a high energy β-emitting radioisotope obtained from the tungsten-188/rhenium-188 (W-188/Re-188) generator, which has shown utility for a variety of therapeutic applications in nuclear medicine, oncology, and interventional radiology/cardiology.
Re-188 decay is accompanied by a 155 keV predominant energy γ-emission, which could be detected by γ-cameras, for imaging, biodistribution, or absorbed radiation dose studies.
Its attractive physical properties and its potential low cost associated with a long-lived parent make it an interesting option for clinical use.
The setup and daily use of W-188/Re-188 generator in hospital nuclear medicine departments are discussed in detail.
The clinical efficacy, for several therapeutic applications, of a variety of Re-188-labeled agents is demonstrated.
The high energy of the β-emission of Re-188 is particularly well suited for effective penetration in solid tumours.
Its total radiation dose delivered to tissues is comparable to other radionuclides used in therapy.
Furthermore, radiation safety and shielding requirements are an important subject of matter.
In the case of bone metastases treatment, therapeutic ratios are presented in order to describe the efficacy of Re-188 usage.
American Psychological Association (APA)
Argyrou, Maria& Valassi, Alexia& Andreou, Maria& Lyra, Maria. 2013. Rhenium-188 Production in Hospitals, by W-188Re-188 Generator, for Easy Use in Radionuclide Therapy. International Journal of Molecular Imaging،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-460794
Modern Language Association (MLA)
Argyrou, Maria…[et al.]. Rhenium-188 Production in Hospitals, by W-188Re-188 Generator, for Easy Use in Radionuclide Therapy. International Journal of Molecular Imaging No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-460794
American Medical Association (AMA)
Argyrou, Maria& Valassi, Alexia& Andreou, Maria& Lyra, Maria. Rhenium-188 Production in Hospitals, by W-188Re-188 Generator, for Easy Use in Radionuclide Therapy. International Journal of Molecular Imaging. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-460794
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-460794